Results 121 to 130 of about 2,092,591 (384)

Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis.

open access: yesJournal of Immunology, 1981
A statistical method was developed for the analysis of experimental data from limiting dilution assays. Formulas for the estimation of the frequency of immunocompetent cells within a test population were derived by the statistical methods of weighted ...
C. Taswell
semanticscholar   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Random site dilution properties of frustrated magnets on a hierarchical lattice

open access: yes, 2012
We present a method to analyze magnetic properties of frustrated Ising spin models on specific hierarchical lattices with random dilution. Disorder is induced by dilution and geometrical frustration rather than randomness in the internal couplings of the
Berker A N   +6 more
core   +2 more sources

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Helium 3/Helium 4 dilution cryocooler for space [PDF]

open access: yes
Prototype dilution cryocoolers based on dilution refrigeration and adiabatic demagnetization refrigeration (ADR) cycles were designed, constructed, and tested.
Dingus, Michael L., Hendricks, John B.
core   +1 more source

Dilution Zone Mixing [PDF]

open access: yes, 1983
Studies to characterize dilution zone mixing; experiments on the effects of free-stream turbulence on a jet in crossflow; and the development of an interactive computer code for the analysis of the mixing of jets with a confined crossflow are ...
Holdeman, J. D.
core   +1 more source

THE INFLUENCE OF GEOLOGY AND ORE DEPOSIT OCCURRENCE CONDITIONS ON DILUTION INDICATORS OF EXTRACTED RESERVES

open access: yesRudarsko-geološko-naftni Zbornik, 2019
The development of iron-ore deposits is accompanied by the excavation formation of considerable dimensions in the underground space and to ensure high technical and economic indicators of extraction, especially when developing high-grade iron ore, it is ...
Mykhailo Petlovanyi   +4 more
doaj   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

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