Results 131 to 140 of about 2,144,368 (379)
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Revue des Énergies Renouvelables, 2016 Cette étude est consacrée à l’évaluation du comportement végétatif des plants maraîchers vis-à-vis des jus de process obtenus après dilution respectivement, du digestat liquide issu d’une installation de biométhanisation rurale bovine, dénommé Jus de ...
Y. M’Sadak, A. Ben M'Barek
doaj
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Study of dilution, height, and lateral spread of vertical dense jets in marine shallow water [PDF]
, 2016 Nadeem Ahmad, Takayuki Suzuki
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Statement to Water Resources Subcommittee of House Committee on Public Works and Transportation for a Hearing, May 24 and 25, 1978, Washington, D.C. regarding Secondary Treatment Waivers and Ocean Outfalls [PDF]
, 1978 The principal technical reason for having a waiver provision for secondary treatment for municipal discharges is that for some outfall systems the dilution is so high that very good ambient water quality can be achieved with less than secondary ...
Brooks, Norman H.
core
Percolation Critical Exponents in Scale-Free Networks
, 2002 We study the behavior of scale-free networks, having connectivity distribution P(k) k^-a, close to the percolation threshold.
D.S. Callaway +16 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source