Results 21 to 30 of about 4,841,679 (193)

THE NATURAL-LEGAL DIMENSION OF A PERSON’S STATUS [PDF]

open access: yesЭлектронное приложение к Российскому юридическому журналу, 2019
The natural law theory of a person as a substance of his own is presented in the article. The author analyzes historical and contemporary theories and states that any human rights and freedoms can be derived only from such a fundamental level, that a ...
Píry Martin
doaj  

The Duration of History in Bergson

open access: yesBergsoniana, 2021
Although he developed one of the most important modern theories of time, Bergson has often been criticised for not thinking history. Drawing on his writings from Creative Evolution to The Two Sources, I show that, on the contrary, he was trying to define
Caterina Zanfi
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Identification of natural fractures using resistive image logs, fractal dimension and support vector machines

open access: yesIngeniería e Investigación, 2016
The purpose of this research is to apply a new approach to identify natural fractures in wells in a hydrocarbon reservoir using resistive image logs, fractal dimension and support vector machines (SVMs).
Jorge Alberto Leal   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Presentación del informe sobre la Dimensión Social en diversos organismos regionales

open access: yes, 2009
ALADI. Comité de Representantes.
ALADI. Comité de Representantes. Grupo de Trabajo sobre la Dimensión Social en el Proceso de Integración de la ALADI
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

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