Results 41 to 50 of about 807,675 (265)

Checkpoint blockade and the stem‐like T cell trade‐off

open access: yesMolecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

El tiempo fragmentado: recorrido entrecruzado entre narración y drama [PDF]

open access: yes, 2016
A la hora de concretar las características de un teatro que mezcle narración y drama, resulta evidente que no se puede establecer un pacto perceptivo rígido: desde el primer momento, la obra de teatro debe introducir a los espectadores en un campo ...
Baliani, Marco
core   +1 more source

El sitio de los dólmenes de Antequera en la obra de Georg y Vera Leisner: una revisión [PDF]

open access: yes, 2019
The Antequera dolmens site (Malaga, Spain), included in the UNESCO World Heritage List since July 2016, has a research history of almost 200 years that goes back to the work of Rafael Mitjana y Ardison in the 1840s.
Bartelheim, Martin   +2 more
core   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

El Conocimiento y la comunicación de la dimensión espiritual dentro de una perspectiva de la especialidad contable socio-ambiental

open access: yesContabilidad y Auditoría, 2015
Se considera importante la emisión de informes contables socio-ambientales para la sustentabilidad y se intenta contribuir a la comprensión de un lineamiento para obtener conocimientos a través de la denominada especialidad contable socio-ambiental.
Norma Beatriz Geba   +2 more
doaj  

Universal Constants and Natural Systems of Units in a Spacetime of Arbitrary Dimension

open access: yesUniverse, 2020
We study the properties of fundamental physical constants using the threefold classification of dimensional constants proposed by J.-M. Lévy-Leblond: constants of objects (masses, etc.), constants of phenomena (coupling constants), and “universal ...
Anton Sheykin, Sergey Manida
doaj   +1 more source

Characterization and Classification of Collaborative Tools [PDF]

open access: yes, 2010
Traditionally, collaboration has been a means for organizations to do their work. However, the context in which they do this work is changing, especially in regards to where the work is done, how the work is organized, who does the work, and with this ...
Fernández Gallego, Rafael   +2 more
core   +2 more sources

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Aesthetic dimension about tropical forest in ecology teaching [PDF]

open access: yesInvestigações em Ensino de Ciências, 2009
The research analyzes the aesthetic dimension on teaching about natural environment on Ecology disciplines. The semiotics of Charles Sanders Peirce guided data analysis, regarding to suggested values on the answers of interviewees.
Tatiana Seniciato   +2 more
doaj  

Bipolar flaking as a component of a supraregional lithic resource base: A comparative study of cores from the Pampean and Northcentral Patagonian Atlantic coasts (Argentina) [PDF]

open access: yes, 2018
Several authors argue that bipolar technology is an expeditious and versatile strategy, efficient for the reduction of small nodules. However, few studies analyze the use of bipolar reduction in relation to the lithic environmental supply. At the Pampean
Banegas, Anahi   +2 more
core   +1 more source

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