Results 51 to 60 of about 807,675 (265)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Rapid Growth of Dimension Stone Imports: Implications for the Urban Geocultural Heritage of the City of Poznań (Poland)

open access: yesGeosciences
The global production of dimension stones, that is, natural stones that can be processed into blocks and used as building and decorative materials, has grown steadily since the second half of the twentieth century.
Paweł Wolniewicz
doaj   +1 more source

Attitudes, Ideological Associations and the Left–Right Divide in Latin America [PDF]

open access: yes, 2012
Do Latin American citizens share a common conception of the ideological left–right distinction? And if so, is this conception linked to individuals’ ideological self-placement?
Doyle, David, Wiesehomeier, Nina
core   +1 more source

La identidad urbana como categoría de anàlisis: una propuesta metodológica para la lectura del territorio a través de la consolidación Histórico-Espacial de sus atributos urbanos característicos [PDF]

open access: yes, 2017
Reconocer la ciudad como una construcción en tiempo y espacio, es clave para una lectura territorial integral, que al combinar diferentes factores, desde la dimensión natural, social e histórico-urbana, permite identificar las condiciones existentes en ...
Herrera Valencia, Ana Cristina
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

On the Removability Property of φ-Natural Domains in Real Banach Spaces

open access: yesJournal of Mathematics, 2022
In this paper, we investigate the removability of φ-natural domains in Banach spaces. Let E be a real Banach space with dimension at least 2, G a domain in E, and let be a countable subset of G which satisfies a quasi hyperbolic separation condition ...
Yuehui He
doaj   +1 more source

Motivación y segmentación del turista en festivales culinarios.El caso de la feria gastronómica en el Parque Natural Sierras de Cazorla, Segura y las Villas (España) [PDF]

open access: yes, 2014
Asociado al espacio natural y al disfrute gastronómico, la Feria del Parque Natural Sierras de Cazorla, Segura y Las Villas (España) expone y comercializa productos agroalimentarios elaborados artesanalmente en este medio natural.
López Guzmán, Tomás   +2 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Fractal Analysis Of Colors And Shapes For Natural And Urbanscapes URBANSCAPES [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015
Fractal analysis has been applied in many fields since it was proposed by Mandelbrot in 1967. Fractal dimension is a basic parameter of fractal analysis.
J. Wang, S. Ogawa
doaj   +1 more source

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