Results 61 to 70 of about 13,553,506 (283)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Rapid Growth of Dimension Stone Imports: Implications for the Urban Geocultural Heritage of the City of Poznań (Poland)

open access: yesGeosciences
The global production of dimension stones, that is, natural stones that can be processed into blocks and used as building and decorative materials, has grown steadily since the second half of the twentieth century.
Paweł Wolniewicz
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Minuta 7 : continuación de los trabajos sobre la matriz de la dimensión Social encomendada por el Grupo a la Secretaría General para la elaboración del Plan de Acción Priorizado de la Dimensión Social

open access: yes, 2009
ALADI. Comité de Representantes.
ALADI. Comité de Representantes. Grupo de Trabajo sobre la Dimensión Social en el Proceso de Integración de la ALADI
core   +1 more source

Algorithmic Information, Plane Kakeya Sets, and Conditional Dimension [PDF]

open access: yesSymposium on Theoretical Aspects of Computer Science, 2015
We formulate the conditional Kolmogorov complexity of x given y at precision r, where x and y are points in Euclidean spaces and r is a natural number.
J. H. Lutz, Neil Lutz
semanticscholar   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

One Pixel Attack for Fooling Deep Neural Networks [PDF]

open access: yesIEEE Transactions on Evolutionary Computation, 2017
Recent research has revealed that the output of deep neural networks (DNNs) can be easily altered by adding relatively small perturbations to the input vector.
Jiawei Su   +2 more
semanticscholar   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Natural genetic variation quantitatively regulates heart rate and dimension

open access: yesNature Communications
The polygenic contribution to heart development and function along the health-disease continuum remains unresolved. To gain insight into the genetic basis of quantitative cardiac phenotypes, we utilize highly inbred Japanese rice fish models, Oryzias ...
Jakob Gierten   +12 more
doaj   +1 more source

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