Results 101 to 110 of about 1,125,791 (311)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

La dimensión social de la empresa

open access: yesRevista Empresa y Humanismo, 2008
La visión dominante de la empresa tiende a centrarse en la ganancia monetaria como única justificación social de la misma. En este artículo se considera necesaria esa condición, pero se ahonda en las condiciones sociales suficientes para considerar la ...
Javier Aranzadi del Cerro
doaj  

Dimensión social del paisaje como herramienta para la gestión de espacios naturales en entornos agrícolas [PDF]

open access: gold, 2019
Minerva Cordovés-Sánchez   +2 more
openalex   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

LA DIMENSIÓN SOCIAL DEL APRENDIZAJE COLABORATIVO

open access: yesRED. Revista de Educación a Distancia, 2007
El objetivo de este artículo es analizar la dimensión social de los grupos colaborativos virtuales. Aunque, a menudo, estos aspectos de carácter informal o afectivo se infravaloran o separan de los propios del aprendizaje, son muy numerosos los estudios ...
Maria Pérez   +2 more
doaj  

Dimensión socio-cultural en Santa Clara del Mar [PDF]

open access: yes, 2015
Santa Clara del Mar es una localidad costera del partido de Mar Chiquita que presenta una compleja dimensión socio-cultural. En este contexto se plantea, qué acciones deberían concertarse entre los diferentes actores sociales en el mediano y largo plazo ...
González, María Graciela
core  

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

¿Influyen las características culturales de los países en la relación entre RSC Y RF? [PDF]

open access: yes, 2011
El objetivo de este trabajo es profundizar en la relación existente entre Responsabilidad Social Corporativa (RSC) y Rendimiento Financiero (RF) estudiando el posible efecto moderador que la variable país, medida a través de las características ...
Carrasco Gallego, Amalia   +2 more
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini   +7 more
wiley   +1 more source

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