Results 71 to 80 of about 4,393,923 (290)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Dimension Reduction for Objects Composed of Vector Sets

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2017
Dimension reduction and feature selection are fundamental tools for machine learning and data mining. Most existing methods, however, assume that objects are represented by a single vectorial descriptor.
Szemenyei Marton, Vajda Ferenc
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Dimension reduction for $-\Delta_1$

open access: yes, 2012
A 3D-2D dimension reduction for $-\Delta_1$ is obtained. A power law approximation from $-\Delta_p$ as $p \to 1$ in terms of $\Gamma$- convergence, duality and asymptotics for least gradient functions has also been provided.
Maria Emilia Amendola   +2 more
openaire   +3 more sources

Dimension Reduction in Nonparametric Discriminant Analysis [PDF]

open access: yes
A dimension reduction method in kernel discriminant analysis is presented, based on the concept of dimension reduction subspace. Examples of application are discussed.
Santiago Velilla, Adolfo Hernández
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

LDR: A Package for Likelihood-Based Sufficient Dimension Reduction [PDF]

open access: yes
We introduce a new mlab software package that implements several recently proposed likelihood-based methods for sufficient dimension reduction. Current capabilities include estimation of reduced subspaces with a fixed dimension d, as well as estimation ...
R. Dennis Cook   +2 more
core  

Error estimation of a proper orthogonal decomposition reduced model of a permanent magnet synchronous machine [PDF]

open access: yes, 2014
Model order reduction methods, like the proper orthogonal decomposition (POD), enable to reduce dramatically the size of a finite element (FE) model.
MAC, Hung   +2 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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