Results 51 to 60 of about 4,596,502 (304)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Study on dimensional stability of ultra-high performance concrete (UHPC) [PDF]

open access: yes, 2020
Ultra-high performance concrete (UHPC), a new cement-based material, has character of superior mechanical properties and excellent durability. Especially, it possesses compressive strength higher than 150 MPa, which is approximately 3 times as that of ...
Wu, Linmei
core  

The Effect of Cryogenic Treatment on Some Chemical, Physical, and Mechanical Properties of Thermowood® Oriental Spruce

open access: yesBioResources, 2022
Effects of cryogenic treatment on the chemical, physical, and mechanical properties of oriental spruce wood, which was heat-treated with the Thermowood® method, were investigated in this work.
Ayhan Aytin   +3 more
doaj  

Effect of Boron Compounds on Properties of Chinese Fir Wood Treated with PMUF Resin

open access: yesJournal of Bioresources and Bioproducts, 2019
Plantation Chinese fir wood was modified by low molecular weight phenol melamine urea formaldehyde (PMUF) resin and boron compounds (BB) through a progressive gradual infiltration process.
Fei Wang, Junliang Liu, Wenhua Lyu
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

High speed machining of aluminium gear box without temperature stabilization [PDF]

open access: yesTransport Problems, 2010
At the present time both clutch and mechanism housings, which are the main components from automotive gear boxes, are made of special aluminium alloys.
Abilio P. SILVA   +3 more
doaj  

Influência da distribuição granulométrica na estabilidade dimensional de placas cerâmicas de base vermelha Influence of particle size distribution on the dimensional stability of red ceramic tiles

open access: yesCerâmica, 2008
As propriedades do revestimento cerâmico queimado estão intrinsecamente ligadas às características da massa, dentre estas se encontram o tamanho, a distribuição, o formato e o arranjo das partículas.
A. C. A. Prado   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Organosilane-modified Wood Materials: A Review of Research and Applications

open access: yesBioResources, 2023
This review article discusses the use of organosilane (OS) compounds and their derivatives to modify wood materials. The emphasis in this work is on trialkoxysilanes and effects of their reactions with hydroxyl groups at wood surfaces.
Honghai Liu   +3 more
doaj  

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