Results 61 to 70 of about 4,596,502 (304)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Tratamiento químico de acetilación en madera de Pinus radiata

open access: yesMaderas: Ciencia y Tecnología, 2014
Al saturar la pared celular de la madera con anhídrido acético, se reemplazan los grupos hi-droxilos libres de las macromoléculas celulosa y hemicelulosa.
R. Garay, M. Henriquez
doaj  

On the Stability of One‐Dimensional Wave Equation [PDF]

open access: yesThe Scientific World Journal, 2013
We prove the generalized Hyers‐Ulam stability of the one‐dimensional wave equation, utt = c2uxx, in a class of twice continuously differentiable functions.
openaire   +3 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Preliminary Investigation of the Suitability of Chasmanthera Dependens (Hosct) and Waste Paper for Production of Cement-Bonded Composite [PDF]

open access: yesPro Ligno, 2017
The physical and mechanical properties of cement bonded board produced from Chasmanthera dependens and waste paper was investigated in this study. Boards were produced at 50:50, 60:40 and 70:30 levels of blending proportions of paper-fiber by weight ...
Kehinde OLONISAKIN   +2 more
doaj  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Robustness of infinite dimensional systems [PDF]

open access: yes
The results contained within this thesis concern an abstract framework for a robustness analysis of exponential stability of infinite dimensional systems.
Townley, Stuart
core  

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