Results 61 to 70 of about 4,596,502 (304)
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Tratamiento químico de acetilación en madera de Pinus radiata
Al saturar la pared celular de la madera con anhídrido acético, se reemplazan los grupos hi-droxilos libres de las macromoléculas celulosa y hemicelulosa.
R. Garay, M. Henriquez
doaj
On the Stability of One‐Dimensional Wave Equation [PDF]
We prove the generalized Hyers‐Ulam stability of the one‐dimensional wave equation, utt = c2uxx, in a class of twice continuously differentiable functions.
openaire +3 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Preliminary Investigation of the Suitability of Chasmanthera Dependens (Hosct) and Waste Paper for Production of Cement-Bonded Composite [PDF]
The physical and mechanical properties of cement bonded board produced from Chasmanthera dependens and waste paper was investigated in this study. Boards were produced at 50:50, 60:40 and 70:30 levels of blending proportions of paper-fiber by weight ...
Kehinde OLONISAKIN +2 more
doaj
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Robustness of infinite dimensional systems [PDF]
The results contained within this thesis concern an abstract framework for a robustness analysis of exponential stability of infinite dimensional systems.
Townley, Stuart
core

