Results 91 to 100 of about 316,362 (306)

DIMENSIONALITY OF BIG DATA SETS EXPLORED BY CLUJ DESCRIPTORS [PDF]

, 2017
Dimensionality of a relatively big data set (95 compounds) observed for toxicity (mutagenicity) was explored in order to compute QSAR models. Distinct molecular descriptors were used.
Atena PÎRVAN-MOLDOVAN, Subhash BASAK, Claudiu N. LUNGU, SZEFLER, Beata, BASAK, Subhash, Mircea V. DIUDEA, Beata SZEFLER, LUNGU, Claudiu N., ERSALI, Sara, DIUDEA, Mircea V., Sara ERSALI, PÎRVAN-MOLDOVAN, Atena   +11 more
core   +1 more source

Benchmarking Variants of Recursive Feature Elimination: Insights from Predictive Tasks in Education and Healthcare

Information
Originally developed as an effective feature selection method in healthcare predictive analytics, Recursive Feature Elimination (RFE) has gained increasing popularity in Educational Data Mining (EDM) due to its ability to handle high-dimensional data and
Okan Bulut, Bin Tan, Elisabetta Mazzullo, Ali Syed   +3 more
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

The Emerging "Big Dimensionality"

, 2014
The world continues to generate quintillion bytes of data daily, leading to the pressing needs for new efforts in dealing with the grand challenges brought by Big Data.
Tsang, Ivor W., Ong, Yew-Soon, Zhai, Yiteng   +2 more
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

The instructional modality used for contextual vertical integration of anatomy influences cognitive load and performance during an operative interpretation task in undergraduate gynaecology students: evidence from a multi-centre cluster-randomised controlled trial

Frontiers in Medicine
IntroductionOperative interpretation is central to the educational value of theatre placements, yet students often struggle to apply preclinical anatomy to the operative setting.
Mohammed Ismail-Khan, Mohammed Ismail-Khan, Mohammed Ismail-Khan, Md. Siddique Ahmed Khan, Jabeen Aslam, Ratna Kumari, Ratna Kumari, Arwa Areej, Ramana Devi, Tallapaneni Sreekanth, Fateen Fatima Mazher, Mohammed Musheer, Porfyrios Korompelis   +12 more
doaj   +1 more source

Changes in Dimensionality and Fractal Scaling Suggest Soft-Assembled Dynamics in Human EEG

Frontiers in Physiology, 2017
Humans are high-dimensional, complex systems consisting of many components that must coordinate in order to perform even the simplest of activities. Many behavioral studies, especially in the movement sciences, have advanced the notion of soft-assembly ...
Travis J. Wiltshire, Travis J. Wiltshire, Matthew J. Euler, Ty L. McKinney, Jonathan E. Butner   +4 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Aplicación del análisis por componentes principales en la evaluación de tres variedades de pasto Aplicação da análise de componentes principais na avaliação de três variedades de capim Application of the principal-component analysis in the evaluation of three grass varieties

Revista Colombiana de Ciencias Pecuarias, 2012
Objetivo: mostrar una aplicación del análisis de componentes principales en la reducción de la dimensionalidad de variables derivadas de la evaluación agronómica de tres variedades de pasto. Métodos: los pastos evaluados fueron Ryegrass (Lolium sp.
Luis F Restrepo, Sandra L Posada, Ricardo R Noguera   +2 more
doaj