Results 91 to 100 of about 8,286,998 (397)

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Non-negative Dimensionality Reduction for Mammogram Classification [PDF]

open access: yesJournal of Electrical and Electronics Engineering, 2009
Directly classifying high dimensional datamay exhibit the ``curse of dimensionality'' issue thatwould negatively influence the classificationperformance with an increase in the computationalload, depending also on the classifier structure.
I. Buciu, A. Gacsadi
doaj  

Tensor Networks for Dimensionality Reduction and Large-scale Optimization: Part 1 Low-Rank Tensor Decompositions [PDF]

open access: yesFound. Trends Mach. Learn., 2016
Modern applications in engineering and data science are increasinglybased on multidimensional data of exceedingly high volume, variety,and structural richness.
A. Cichocki   +5 more
semanticscholar   +1 more source

Spectral dimensionality reduction for HMMs [PDF]

open access: yes, 2012
Hidden Markov Models (HMMs) can be accurately approximated using co-occurrence frequencies of pairs and triples of observations by using a fast spectral method in contrast to the usual slow methods like EM or Gibbs sampling.
Foster, Dean P.   +2 more
core   +2 more sources

Sequential Dimensionality Reduction for Extracting Localized Features

open access: yes, 2016
Linear dimensionality reduction techniques are powerful tools for image analysis as they allow the identification of important features in a data set. In particular, nonnegative matrix factorization (NMF) has become very popular as it is able to extract ...
Casalino, Gabriella, Gillis, Nicolas
core   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

DROP: Dimensionality Reduction Optimization for Time Series

open access: yes, 2019
Dimensionality reduction is a critical step in scaling machine learning pipelines. Principal component analysis (PCA) is a standard tool for dimensionality reduction, but performing PCA over a full dataset can be prohibitively expensive.
Bailis, Peter, Suri, Sahaana
core   +1 more source

Adaptive Metric Dimensionality Reduction [PDF]

open access: yesTheoretical Computer Science, 2013
We study adaptive data-dependent dimensionality reduction in the context of supervised learning in general metric spaces. Our main statistical contribution is a generalization bound for Lipschitz functions in metric spaces that are doubling, or nearly doubling.
Aryeh Kontorovich   +2 more
openaire   +4 more sources

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Reduction algorithm based on supervised discriminant projection for network security data

open access: yesTongxin xuebao, 2021
In response to the problem that for dimensionality reduction, traditional manifold learning algorithm did not consider the raw data category information, and the degree of clustering was generally at a low level, a manifold learning dimensionality ...
Fangfang GUO   +3 more
doaj   +2 more sources

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