Results 71 to 80 of about 141,001 (306)

Nonlinear dimensionality reduction in climate data [PDF]

open access: yesNonlinear Processes in Geophysics, 2004
Linear methods of dimensionality reduction are useful tools for handling and interpreting high dimensional data. However, the cumulative variance explained by each of the subspaces in which the data space is decomposed may show a slow convergence that ...
A. J. Gámez   +3 more
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Nonlinear Dynamic Field Embedding: On Hyperspectral Scene Visualization [PDF]

open access: yes, 2012
In many areas of research, complex signals are commonly represented by high dimensional feature vectors. However, high dimensional vectors are difficult to analyze and interpret due to the curse of dimensionality.
Lunga, Dalton, Erosy, Okan
core   +1 more source

Dimensionality reduction methods. [PDF]

open access: yes, 2019
Dimensionality reduction methods.
Susan Holmes (243177)   +1 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Nonlinear Dimensionality Reduction Based on HSIC Maximization

open access: yesIEEE Access, 2018
Hilbert-Schmidt independence criterion (HSIC) is typically used to measure the statistical dependence between two sets of data. HSIC first transforms these two sets of data into two reproducing Kernel Hilbert spaces (RKHS), respectively, and then ...
Zhengming Ma   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Dimensionality reduction of massive sparse datasets using coresets [PDF]

open access: yes, 2019
© 2016 NIPS Foundation - All Rights Reserved. In this paper we present a practical solution with performance guarantees to the problem of dimensionality reduction for very large scale sparse matrices. We show applications of our approach to computing the
Feldman, Dan   +2 more
core  

AUC results of EDTMDA between with dimensionality reduction and without dimensionality reduction under three cross validations. [PDF]

open access: yes, 2019
AUC results of EDTMDA between with dimensionality reduction and without dimensionality reduction under three cross validations.
Jun Yin (94374)   +2 more
core   +1 more source

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