Results 51 to 60 of about 379,758 (236)
Randomized Dimensionality Reduction for k-means Clustering [PDF]
, 2013 We study the topic of dimensionality reduction for $k$-means clustering. Dimensionality reduction encompasses the union of two approaches: \emph{feature selection} and \emph{feature extraction}.
Boutsidis, Christos +3 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Non‐linear dimensionality reduction using fuzzy lattices
IET Computer Vision, 2013 The proposed method is based on extraction of non‐linearity from the nearest neighbourhood elements of image. To detect non‐linearity, relation between the nearest neighbourhood elements of the image, have been expressed in terms of Gaussian membership ...
Rajiv Kapoor, Rashmi Gupta
doaj +1 more source
Dimensionality Reduction in Gene Expression Data Sets
IEEE Access, 2019 Dimensionality reduction is used in microarray data analysis to enhance prediction quality, reduce computing time, and construct more robust models.
Jovani Taveira De Souza +2 more
doaj +1 more source
Detecting Adversarial Examples through Nonlinear Dimensionality Reduction [PDF]
, 2019 Deep neural networks are vulnerable to adversarial examples, i.e., carefully-perturbed inputs aimed to mislead classification. This work proposes a detection method based on combining non-linear dimensionality reduction and density estimation techniques.
Bacciu, Davide +2 more
core +1 more source
Quantum Discriminant Analysis for Dimensionality Reduction and Classification
, 2016 We present quantum algorithms to efficiently perform discriminant analysis for dimensionality reduction and classification over an exponentially large input data set.
Cong, Iris, Duan, Luming
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Morphological mapping for non‐linear dimensionality reduction
IET Computer Vision, 2015 Recently, much research has been carried out on dimensionality reduction techniques that summarise a large set of features into a smaller set, leading to much less redundancy.
Rajiv Kapoor, Rashmi Gupta
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source