Results 41 to 50 of about 379,758 (236)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Non-Redundant Spectral Dimensionality Reduction
, 2017 Spectral dimensionality reduction algorithms are widely used in numerous domains, including for recognition, segmentation, tracking and visualization.
A Brun +26 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Dimensionality reduction method for hyperspectral image analysis based on rough set theory
European Journal of Remote Sensing, 2020 High-dimensional features often cause computational complexity and dimensionality curse. Feature selection and feature extraction are the two mainstream methods for dimensionality reduction.
Zhenhua Wang +5 more
doaj +1 more source
Dimensionality Reduction by Similarity Distance-Based Hypergraph Embedding
Atmosphere, 2022 Dimensionality reduction (DR) is an essential pre-processing step for hyperspectral image processing and analysis. However, the complex relationship among several sample clusters, which reveals more intrinsic information about samples but cannot be ...
Xingchen Shen, Shixu Fang, Wenwen Qiang
doaj +1 more source
Nonlinear Supervised Dimensionality Reduction via Smooth Regular Embeddings
, 2018 The recovery of the intrinsic geometric structures of data collections is an important problem in data analysis. Supervised extensions of several manifold learning approaches have been proposed in the recent years.
Ornek, Cem, Vural, Elif
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Nonlinear Dimensionality Reduction Based on HSIC Maximization
IEEE Access, 2018 Hilbert-Schmidt independence criterion (HSIC) is typically used to measure the statistical dependence between two sets of data. HSIC first transforms these two sets of data into two reproducing Kernel Hilbert spaces (RKHS), respectively, and then ...
Zhengming Ma +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
BIP: A dimensionality reduction for image indexing
ICT Express, 2019 Searching on internet is one of the daily task done by millions of users around the Globe. There is an urge for effective indexing scheme for unstructured data, which provide better search results. The image, content report, and site pages are said to be
Minu R.I. +3 more
doaj +1 more source