Results 121 to 130 of about 3,322,529 (303)

Multiple Kernel Spectral Regression for Dimensionality Reduction

open access: yesJournal of Applied Mathematics, 2013
Traditional manifold learning algorithms, such as locally linear embedding, Isomap, and Laplacian eigenmap, only provide the embedding results of the training samples.
Bing Liu, Shixiong Xia, Yong Zhou
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Certifying Entanglement Dimensionality by k-Reduction Moments

open access: yesPRX Quantum
In this paper, we combine the k-reduction map, the moment method, and randomized measurements into a practical protocol for certifying the entanglement dimensionality. Our approach is based on the observation that a state with entanglement dimensionality
Changhao Yi, Xiaodi Li, Huangjun Zhu
doaj   +1 more source

Chapter 4 Dimensionality reduction

open access: yes, 2008
This chapter introduces and defines the problem of dimensionality reduction, discusses the topics of the curse of the dimensionality and the intrinsic dimensionality and then surveys non-probabilistic methods for dimensionality reduction, that is ...

core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Dimensionality reduction on vector spaces using complex random matrices

open access: yes
reservedIn this thesis we present part of a wider work regarding dimensionality reduction on the Euclidean space. Specifically we focus on finding concentration bounds for sums of Rademacher Chaoses.
MORETTI, SIMONE
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Dimensionality reduction for predicting student performance in unbalanced data sets [PDF]

open access: yes, 2019
In this study, we evaluated two data sets from two Portuguese schools for predicting student performance. These data sets contain not only the previous grades of the students, but also the demographic, social and school related features. Both data sets
Khor, Kok Chin   +2 more
core   +1 more source

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