Results 131 to 140 of about 139,695 (308)

A note on the choice of the number of slices in sliced inverse regression [PDF]

open access: yes
Sliced inverse regression (SIR) is a clever technique for reducing the dimension of the predictor in regression problems, thus avoiding the curse of dimensionality. There exist many contributions on various aspects of the performance of SIR.
Gather, Ursula, Becker, Claudia
core  

Multilabel dimensionality reduction via dependence maximization

open access: yes, 2010
Multilabel learning deals with data associated with multiple labels simultaneously. Like other data mining and machine learning tasks, multilabel learning also suffers from the curse of dimensionality . Dimensionality
Zhi-Hua Zhou, Yin Zhang
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Dimensionality Reduction

open access: yes, 2008
Dimensionality reduction studies methods that effectively reduce data dimensionality for efficient data process-ing tasks such as pattern recognition, machine learning, text retrieval, and data mining.
Huan Liu, Manoranjan Dash
core  

Unsupervised shape clustering using diffusion map [PDF]

open access: yes, 2008
The quotient space of all smooth and connected curves represented by a fixed number of boundary points is a finite-dimensional Riemannian manifold, also known as a shape manifold.
Rajpoot, Nasir M. (Nasir Mahmood)   +1 more
core  

Semi-supervised nonlinear dimensionality reduction

open access: yes, 2006
The problem of nonlinear dimensionality reduction is considered. We focus on problems where prior information is available, namely, semi-supervised dimensionality reduction.
Xin Yang   +3 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Robust Structure Preserving Nonnegative Matrix Factorization for Dimensionality Reduction

open access: yes, 2016
As a linear dimensionality reduction method, nonnegative matrix factorization (NMF) has been widely used in many fields, such as machine learning and data mining.
Li BF(李冰锋)   +2 more
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

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