Results 231 to 240 of about 679,917 (339)

Similarity in transcytosis of nNOSα in enteric nerve terminals and beta cells of pancreatic islet

Frontiers in Medicine, 2014
ARUN eCHAUDHURY
doaj   +1 more source

Unconventional bipartite entanglement in the quantum dimer magnet Yb₂Be₂SiO₇. [PDF]

Nat Commun
Brassington A, Ma Q, Duan G, Calder S, Kolesnikov AI, Taddei KM, Sala G, Choi ES, Wang H, Xie W, Frandsen BA, Li N, Sun XF, Liu C, Yu R, Zhou HD, Aczel AA.   +16 more
europepmc   +1 more source

Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) activate NF‐κB and provoke inflammation that limits therapeutic delivery. By encapsulating selective NF‐κB inhibitors within LNPs, localized suppression of inflammatory signaling is achieved without compromising mRNA expression.
Carolann L. Espy, Jichuan Wu, Serena Omo‐Lamai, Liuqian Wang, Fengyi Dong, Aleksa Milosavljevic, Sarah O'Neill, Taylor Brysgel, Yufei Wang, Michael Zaleski, Emily Wolfe, Rhea Maheshwari, Manthan Patel, Dirk Trauner, Jia Nong, Zhicheng Wang, Jacob S. Brenner   +16 more
wiley   +1 more source

Dimeric Polyphenol Effect on Liquid-Ordered and Liquid-Disordered Membranes: Combined Insights from Molecular Dynamics Simulation and Langmuir Balance Measurements. [PDF]

Langmuir
Wang R, Heinonen S, Vuorimaa-Laukkanen E, Li C, Viitala T, Bunker A.   +5 more
europepmc   +1 more source

Environment Responsive Peptide Dimers Bind and Stabilize dsRNA

Niall M. McLoughlin, Marvin A. Albers, Estel Collado Camps, Jannik Paulus, Youri A. Ran, Saskia Neubacher, Sven Henning, Roland Brock, Tom N. Grossmann   +8 more
openalex   +1 more source

Multiconfiguration Pair-Density Functional Theory: A Fully Translated Gradient Approximation and Its Performance for Transition Metal Dimers and the Spectroscopy of Re₂Cl₈^2–

, 2015
Rebecca K. Carlson, Donald G. Truhlar, Laura Gagliardi   +2 more
openalex   +2 more sources

Engineered Bacteria Factory Integrating Drug Delivery and Antibody Manufacture for Activating the STING Signal Pathway Mediated Tumor Immunotherapy

Advanced Science, EarlyView.
To address the limitations of protein‐based ICIs in applications, this study constructed an engineered bacterium, HRB, capable of expressing aCD47 in hypoxic TME. Through the Schiff base reaction, responsive liposomes (LC) loaded with the STING agonist cGAMP were connected to the surface of bacteria to form HRB@LC.
Peng‐Shuo Dong, Tian Yao, Yong Li, Zi‐Hui Yan, Xiao‐Ting Xie, Jia‐Hua Zou, Kai Cheng, Jin‐Xuan Fan, Yuan‐Di Zhao, Qiu‐Ran Xu   +9 more
wiley   +1 more source

Free energy profile of eviction of H2A/H2B dimer from nucleosome

, 2019
Hisashi Ishida, Hidetoshi Kono, Hisashi Ishida, Hidetoshi Kono   +3 more
openalex   +1 more source

A Photothermal Transducer Regulates Transmembrane Calcium Flow for Synergistic Osteoarthritis Therapy

Advanced Science, EarlyView.
Upon NIR irradiation at 808 nm, the activity of TRPV4 was inhibited by M2M@BPSC, which led to reduced calcium influx, mitochondrial protection, and, importantly, the transcriptional activation of the STAT6‐EGR2 pathway. The improved macrophage function indirectly readjusts the equilibrium between C‐ECM and F‐ECM to reconstruct a suitable ...
Chenqi Yu, Yang Liu, Kang Kang, Jianfeng Yu, Xiaowei Xia, Yaoge Deng, Yingjie Lu, Huilin Yang, Lisong Li, Wu Xu, Yijian Zhang, Xuesong Zhu   +11 more
wiley   +1 more source