Results 41 to 50 of about 1,370 (176)
Inhibition of Bacterial Adherence on the Surface of Stents and Bacterial Growth in Bile by Bismuth Dimercaprol [PDF]
Bacterial infection and biofilm formation on the surface of biliary stents is believed to be one of the main factors in stent occlusion. This study explored the role of the new reagent, bismuth dimercaprol, in preventing bacterial adherence and bacterial
Zhang, Hongjun +4 more
core +1 more source
Actinium-225 (225Ac) is a promising radionuclide used in targeted alpha therapy (TAT). Although 225Ac labeling of bifunctional chelating ligands is effective, previous in vivo studies reported that free 225Ac can be released from the drugs and that such ...
Mitsuyoshi Yoshimoto +11 more
doaj +1 more source
Pharmacological investigations on current and new drugs for treatment of human African trypanosomiasis [PDF]
Trypanosomiasis remains a major threat to humans in sub-Saharan Africa with 55-60 million people in 36 countries at risk of infection with T.b. gambiense or T.b. rhodesiense.
Keiser, Jennifer
core +1 more source
Intoxicación por plomo y su tratamiento farmacologico
La intoxicación por plomo es un problema de salud pública. La evidencia de poblaciones afectadas por niveles tóxicos de plomo en sangre, confirma que hay que seguir trabajando desde una visión pluridisciplinar.
Daniela Fontana +5 more
doaj +1 more source
Advances in Treatment of Wilson Disease
Background: Wilson disease (WD) is an inherited neurometabolic disorder that results in excessive copper deposition in the liver and the brain, affecting children and young adults. Without treatment the disease is invariably fatal.
Annu Aggarwal, Mohit Bhatt
doaj +1 more source
ABSTRACT Mitochondria serve as cellular powerhouses that generate ATP via electron transport chain complexes and orchestrate metabolism‐apoptosis cross‐talk, yet genes maintaining mitochondrial homeostasis remain underexplored as antifungal targets. In this study, a previously uncharacterised protein VdAtuA3 was identified as a novel interactor with ...
Ruo‐Cheng Sheng +10 more
wiley +1 more source
A redox‐active conductive carrier of tannic acid‐modified iron‐biochar with superior wettability is demonstrated to regulate direct electron transfer at the anaerobic biofilm‐carrier interface by enhancing the cytochrome c‐mediated pathway. For the first time, integrated evidence from spectroscopy, electrochemical analyses, and metatranscriptomics ...
Junli Tian +5 more
wiley +1 more source
ABSTRACT We developed a comprehensive, mechanistic model of human copper metabolism to support biomarker qualification for VTX‐801, an adeno‐associated vector‐based gene therapy which is being developed to restore the mutated ATP7B copper transporter gene in Wilson disease (WD). The model integrates physiological copper kinetics with pathophysiological
Andreas Lindauer +3 more
wiley +1 more source
Diagnóstico e tratamento da intoxicação por chumbo em crianças e adultos
O diagnóstico clínico da intoxicação por chumbo deve levar em conta os órgãos-alvo que determinam os sinais e sintomas mais característicos da intoxicação: cérebro, sistema hematopoiético, rins, e sistema nervoso periférico.
Eduardo M. Capitani
doaj +1 more source
Observations on Dithiols and the Distribution of Lead in Rabbits
Summary The influence of several dithiols on the acute distribution and excretion of lead salts has been studied in rabbits. Dimercaprol glucoside and 1:2-dimercaptopropionic acid were substantially more effective than dimercaprol in ...
M Weatherall, K R Adam
core +1 more source

