Results 181 to 190 of about 295,838 (293)

Isolation and Reactivity of a Square‐Planar Trisamido Silane

Angewandte Chemie, EarlyView.
We report the synthesis and comprehensive characterisation of a square‐planar Si(+IV) hydride supported by an unsymmetric, trianionic and dearomatised N,N,N‐pincer ligand. This system enables element–ligand cooperative reactivity as an alternative to silicon‐centred redox chemistry, illuminating a largely unexplored regime in high‐valent silicon ...
David M. J. Krengel, Xiaobai Wang, Christopher Golz, Regine Herbst‐Irmer, Oliver P. E. Townrow, Malte Fischer   +5 more
wiley   +2 more sources

Analysis of the Modulation of RAF Signaling by 14-3-3 Proteins. [PDF]

Bull Math Biol
Carlip P, Stites EC.
europepmc   +1 more source

New Tocopherol Dimers. [PDF]

Acta Chemica Scandinavica, 1968
J. Lars G. Nilsson, G. Doyle Daves, Jr., Karl Folkers, Salo Gronowitz, Harald Christiansen, Ulf Rosén   +5 more
openaire   +2 more sources

Structural basis of Neisseria meningitidis quinol dependent nitric oxide reductase activation by dimerization. [PDF]

Commun Biol
Gopalasingam CC, Egami H, Shigematsu H, Sakaue M, Fukumoto K, Gerle C, Yamamoto M, Shiro Y, Muramoto K, Tosha T.   +9 more
europepmc   +1 more source

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

Advanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer, Steffen Honrath, Jonas Kurmann, Alexander Klipp, Finn Brigger, Jean‐Christophe Leroux   +5 more
wiley   +1 more source

Merging Biocatalysis and Chemocatalysis in Flow: State‐of‐the‐Art and Future Directions for Sustainable Synthesis

Angewandte Chemie, EarlyView.
This review highlights recent advances in integrating biocatalysis and chemocatalysis in continuous flow to create streamlined, sustainable processes. It examines chemo‐enzymatic cascades combining at least one enzymatic and one chemical step, discusses challenges such as enzyme immobilization, leaching, and reactor clogging, and presents solutions ...
Petros Siasiaridis, Matteo Damian, Francesco G. Mutti   +2 more
wiley   +2 more sources

Synthesis and LCMS Characterization of a 1275-Member Library of 24-Atom Triazine Macrocycles Derived from Quantitative Dimerization Occurring with >99.9% Fidelity. [PDF]

ACS Med Chem Lett
Claton LE, Reddy KHV, Gaines SN, Brown SD, Schluckwerder BC, Elam GT, Gendler DS, Ganz AS, McPhaul LC, Rangel AE, Noland JK, Jackson FA, Bobo GG, Yusufji AJ, Simanek EE, Lee KM.   +15 more
europepmc   +1 more source

Dimerization [PDF]

, 2020
openaire   +1 more source

Aggregation‐State Dynamics Drive Double Cooperativity Between Antimicrobial Peptides LL‐37 and HNP1

Angewandte Chemie, EarlyView.
The double cooperative effect between LL‐37 and HNP1 arises from dynamic changes in their aggregation state. These LL‐37/HNP1 assemblies reorganize in a target‐dependent manner, suppressing activity toward mammalian cells while enabling potent antibacterial action.
Yuge Hou, Jing Zhang, Koh Takeuchi, Hideo Higuchi, Motoshi Kaya, Rui Li, Jianlu Zheng, Jiali Chen, Go Watanabe, Kaori Sugihara   +9 more
wiley   +2 more sources

The Role of Cholesterol at the CHOL2 Site and the Dimeric Interface in the Regulation of Serotonin Transporter Function and Dimerization. [PDF]

Biomolecules
Yang J, Li C, Huang X, Zhang YW.
europepmc   +1 more source