Results 201 to 210 of about 197,285 (307)

Molecular basis of Arabidopsis ABCC2 in plant detoxification. [PDF]

Cell Discov
Dong J, Yang TL, Yu XH, Hu KX, Xu LP, Jiang YG, Lin HY, Yang GF.   +7 more
europepmc   +1 more source

Molecular Mechanisms of KIT Receptor Dimerization and Oncogenic Activation Revealed by Multiscale Simulations. [PDF]

J Chem Inf Model
Chiariello MG, Biswas AD, Gratteri C, Prandi IG, Marrink SJ, Beccari A, Talarico C.   +6 more
europepmc   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

Planar cell polarity complex internalization is dependent on Celsr1 <i>cis</i>-dimerization. [PDF]

iScience
Latario SG, Saba T, Trejo B, Giang W, Zimmer SE, Devenport D, Stahley SN.   +6 more
europepmc   +1 more source

Structural Basis of Lymphangiogenic Receptor VEGFR‐3 Activation Mediated by Distinctive Clustering of the Ligand–Receptor Complex

Advanced Science, EarlyView.
VEGF‐C and its receptor VEGFR‐3 are critical for lymphangiogenesis. Cryo‐EM structures of the VEGFR‐3/VEGF‐C ectodomain complex reveal a canonical 2:2 ligand–receptor hetero‐tetramer that further assembles into higher‐order clusters beyond simple receptor dimerization.
Ryeongeun Cho, Jinsook Ahn, Jimin Yang, Dong Sun Lee, Gahi Hong, Sangkyu Lee, Ho Min Kim   +6 more
wiley   +1 more source

TMS-Diazomethane-Mediated Thione Dimerization Enables Access to Photoconvertible Diazaxanthilidene Dyes for Live-Cell Imaging. [PDF]

Org Lett
de Albuquerque JLP, Johnny CL, Raizen LG, Ribagorda M, Chenoweth DM.   +4 more
europepmc   +1 more source

Electrically Tuning Electromagnetic Wave Shielding in Phase Engineered 1T/2H‐MoS2‐Based Devices

Advanced Electronic Materials, EarlyView.
Sub‐millimeter‐thick phase‐engineered 1T/2H‐MoS2 structures enable electrically tunable electromagnetic interference shielding through active modulation of microwave absorption and reflection. The coexistence of metallic and semiconducting phases, combined with a PVA/KOH gel electrolyte, provides dynamic control over charge transport and interfacial ...
Mustafa Akyol, Atalay Bozdogan, Hakan Eroglu, Muharrem Karaaslan   +3 more
wiley   +1 more source

Pathogenic variants in the human TONSL protein associated with SPONASTRIME dysplasia impair protein dimerization and DNA repair. [PDF]

Sci Adv
Karmakar A, Roy S.
europepmc   +1 more source

Deciphering Intricacies in Directional CO2 Conversion From Electrolysis to CO2 Batteries

Advanced Energy Materials, EarlyView.
This review will delve into the inherent connections and distinctions of CO2‐directed conversion in ECO2RR and CO2 batteries, in terms of product types, catalyst selection, catalytic mechanisms, and electrochemical performances, while proposing a benchmarking framework for the evaluation of CO2 batteries and innovative CO2 battery configurations for ...
Changfan Xu, Huaping Zhao, Lizhuang Chen, Weidong Shi, Guosheng Shao, Yong Lei   +5 more
wiley   +1 more source

Immunoglobulin binding protein (BiP) forms two types of dimers. [PDF]

Protein Sci
New K, Lagos-Espinoza MIA, Casanova-Morales N, Asor R, Young JW, Alavi Z, Wilson CAM.   +6 more
europepmc   +1 more source