Results 21 to 30 of about 255,128 (252)

3-[1-(3-Hydroxybenzyl)-1H-benzimidazol-2-yl]phenol dimethyl sulfoxide monosolvate

Acta Crystallographica Section E, 2012
Crystals of the title compound were obtained as a 1:1 dimethyl sulfoxide solvate, C20H16N2O2·C2H6O. The molecular conformation of the organic molecule is similar to that in the previously reported unsolvated structure [Eltayeb et al.
Magdalena Quezada-Miriel, Alcives Avila-Sorrosa, Juan Manuel German-Acacio, Reyna Reyes-Martínez, David Morales-Morales   +4 more
doaj   +1 more source

(E)-6-Bromo-3-{2-[2-(2-chlorobenzylidene)hydrazinyl]thiazol-5-yl}-2H-chromen-2-one dimethyl sulfoxide monosolvate

Acta Crystallographica Section E, 2011
In the title compound C19H11N3O2SClBr·C2H6OS, the molecule adopts an E configuration about the central C=N double bond. The chromene ring system and the thiazole ring are approximately planar, with maximum deviations of 0.027 (2) and 0.
Afsheen Arshad, Hasnah Osman, Chan Kit Lam, Madhukar Hemamalini, Hoong-Kun Fun   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

4-Amino-3-[2-(9H-carbazol-9-yl)ethyl]-1H-1,2,4-triazole-5(4H)-thione dimethyl sulfoxide monosolvate

IUCrData, 2016
In the crystal of the title compound, C16H15N5S·C2H6OS, both the 1,2,4-triazole derivative molecules and the disordered [refined occupancy ratio = 0.604 (1):0.396 (1)] dimethyl sulfoxide solvent molecules form centrosymmetric dimers, by way of pairwise N—
Joel T. Mague, Shaaban K. Mohamed, Mehmet Akkurt, Talaat I. El-Emary, Mustafa R. Albayati   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Di-μ-oxido-bis({2-[(R,R)-(−)-(2-aminocyclohexyl)iminomethyl]-4-nitrophenolato-κ3N,N′,O}oxidovanadium(V)) dimethyl sulfoxide disolvate

Acta Crystallographica Section E, 2009
The title compound, [V2(C13H16N3O3)2O4]·2C2H6OS, is a centrosymmetric dimeric complex solvated by two dimethyl sulfoxide molecules. Each VV atom is six-coordinated by one oxide group, two N atoms and one O atom from the tridentate Schiff base ligand,
Grzegorz Romanowski, Michał Wera, Artur Sikorski   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Cryopreservation of tendon tissue using dimethyl sulfoxide combines conserved cell vitality with maintained biomechanical features.

PLoS ONE, 2019
Biomechanical research on tendon tissue evaluating new treatment strategies to frequently occurring clinical problems regarding tendon degeneration or trauma is of expanding scientific interest.
Eva Hochstrat, Marcus Müller, Andre Frank, Philipp Michel, Uwe Hansen, Michael J Raschke, Daniel Kronenberg, Richard Stange   +7 more
doaj   +1 more source

[1,2-Bis(diphenylphosphanyl)ethane-κ2P,P′]dichloridopalladium(II) dimethyl sulfoxide monosolvate

Acta Crystallographica Section E, 2012
In the title compound, [PdCl2(C26H24P2)]·C2H6OS, the PdII atom adopts a distorted cis-PdCl2P2 square-planar coordination geometry. The five-membered chelate ring adopts an envelope conformation with a methylene C atom in the flap position. The S
Ismail Warad, Abdullah S. Aldwayyan, Fahad M. Al-Jekhedab, M. Iqbal Choudhary, Sammer Yousuf   +4 more
doaj   +1 more source