Results 41 to 50 of about 384,969 (287)

Dimethyl sulfoxide stability of DGAS.

, 2018
Dimethyl sulfoxide stability of DGAS.
Dong-Ho Seo (5403617), Nam-In Baek (536647), Dae-Ok Kim (5875733), Byung-Hoo Lee (397093), Se-Won Jang (5988110), Tae-Gyu Nam (5988122), Chi Heung Cho (5988113), Hee Soon Shin (5988128), Yeong-Geun Lee (5988125), Cheon-Seok Park (2674579), So-Young Lee (554074), Young-Sung Jung (5988116), Chansu Rha (5988119)   +12 more
core   +1 more source

1-Ethyl-4′-(1H-indol-3-ylcarbonyl)-1′-methyl-2,2′′-dioxodispiro[indoline-3,2′-pyrrolidine-3′,3′′-indoline]-4′-carbonitrile dimethyl sulfoxide monosolvate

Acta Crystallographica Section E, 2013
In the title compound, C31H25N5O3·C2H6OS, the three indole/indoline units are all essentially planar with maximum deviations of 0.0172 (3), 0.053 (2) and 0.07 (2) Å.
Paramasivam T. Perumal, K. Sethusankar, S. Antony Inglebert, Yuvaraj Arun   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Bis(4-carboxypyridine-2-carboxylato-κ2N,O2)copper(II) dimethyl sulfoxide disolvate

Acta Crystallographica Section E, 2011
In the title complex, [Cu(C7H4NO4)2]·2C2H6OS, the CuII atom is situated on an inversion centre and is N,O-chelated by two monoanionic 4-carboxypyridine-2-carboxylate ligands in a slightly distorted square-planar coordination geometry.
Hossein Aghabozorg, Saba Goodarzi, Masoud Mirzaei, Behrouz Notash   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A novel approach to separation of waste printed circuit boards using dimethyl sulfoxide [PDF]

, 2013
Waste printed circuit boards are complex heterogeneous mixture consisting of organic material, metal and glass fiber, therefore, it is quite difficult for the recovery of valuable materials from waste printed circuit boards.
Chen, Y., Zhu, P., Zhou, M., Qian, G.R., Wang, L.Y., Zhou, J.   +5 more
core   +3 more sources

9-(5-Bromo-1H-indol-3-yl)-1,2,3,4,5,6,7,8,9,10-decahydroacridine-1,8-dione dimethyl sulfoxide monosolvate

Acta Crystallographica Section E, 2012
In the title compound, C21H19BrN2O2·C2H6OS, the indole ring system is essentially planar, with a maximum deviation of 0.050 (3) Å for the non-bridgehead C atom adjacent to the N atom.
Ahmed El-Khouly, Sema Öztürk Yildirim, Ray J. Butcher, Rahime Şimsek, Cihat Şafak   +4 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

(2-{[4-(Chloridomercuryl)phenyl]iminomethyl}pyridine-κ2N,N′)diiodidomercury(II) dimethyl sulfoxide monosolvate

Acta Crystallographica Section E, 2013
The title dimethyl sulfoxide solvate, [Hg2(C12H9ClN2)I2]·C2H6OS, features tetrahedrally and linearly coordinated HgII atoms. The distorted tetrahedral coordination sphere is defined by chelating N atoms that define an acute angle [69.6 (3 ...
Edward R. T. Tiekink, Seik Weng Ng, Imliwati Longkumer, Tushar S. Basu Baul   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source