Results 71 to 80 of about 381,080 (296)

Bis{μ-2,2′-[(3-azapentane-1,5-diyl)bis(nitrilomethylidyne)]diphenolato}dicopper(II) dimethyl sulfoxide disolvate

Acta Crystallographica Section E, 2008
The title compound, [Cu2(C18H19N3O2)2]·2C2H6OS or [Cu2(SalenN3H)2]·2DMSO, where SalenN3H is the multidentate Schiff base 2,2′-[(3-azapentane-1,5-diyl)bis(nitrilomethylidyne)]diphenolate dianion and DMSO is dimethyl sulfoxide, is a ...
Yasmi Reyes-Ortega, José Luis Alcántara-Flores, Sylvain Bernès, Carmen María González Álvarez, Guadalupe Quintero-Tellez   +4 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Diaqua[(E)-2-(2-oxidobenzylideneamino)-2-phenylacetato]zinc(II) dimethyl sulfoxide monosolvate

Acta Crystallographica Section E, 2009
In the title compound, [Zn(C15H11NO3)(H2O)2]·C2H6OS, the Zn(II) ion is coordinated by two O atoms and one N atom of the deprotonated chelate ligand and two water molecules in a distorted trigonal bipyramidal coordination environment.
Jun You, Bo Liu, Yu-Jing Pang, Qing-Cui Wu   +3 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

1,5-Bis[(E)-1-(2-hydroxyphenyl)ethylidene]carbonohydrazide dimethyl sulfoxide solvate

Acta Crystallographica Section E, 2009
The title dimethyl sulfoxide (DMSO) solvate, C17H18N4O3·C2H6OS, shows the disubstituted urea derivative to adopt an almost planar geometry (r.m.s.
Julio Zukerman-Schpector, Md. Abu Affan, Siong Wan Foo, Edward R. T. Tiekink   +3 more
doaj   +1 more source

The influence of reaction conditions on the Diels-Alder cycloadditions of 2-thio-3-chloroacrylamides; investigation of thermal, catalytic and microwave conditions [PDF]

, 2010
The Diels-Alder cycloadditions of cyclopentadiene and 2,3-dimethyl-1,3-butadiene to a range of 2-thio-3-chloroacrylamides under thermal, catalytic and microwave conditions is described.
Chopra, Jay, Kissane, Marie, Lawrence, Simon E., Lynch, Denis, Maguire, Anita R.   +4 more
core   +1 more source

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

cis-Bis(2,2′-bipyridine-κ2N,N′)bis(dimethyl sulfoxide-κO)zinc bis(tetraphenylborate) dimethyl sulfoxide monosolvate

Acta Crystallographica Section E, 2011
In the mononuclear title complex, [Zn(C10H8N2)2(C2H6OS)2](C24H20B)2·C2H6OS, the ZnII ion is coordinated by four N atoms of two bidentate 2,2′-bipyridine molecules and by the O atoms of two cis-disposed dimethyl sulfoxide molecules in a
Stefania Tomyn, Elżbieta Gumienna-Kontecka, Natalia I. Usenko, Turganbay S. Iskenderov, Elena V. Prisyazhnaya   +4 more
doaj   +1 more source

The effect of dimethyl sulfoxide on the sporicidal activity of ethylene oxide gas [PDF]

Effect of dimethyl sulfoxide on sporicidal activity of ethylene oxide ...
Spiner, D. R.
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source