Results 1 to 10 of about 404 (101)

3,5‐Dinitrobenzoate and 3,5‐Dinitrobenzamide Derivatives: Mechanistic, Antifungal, and In Silico Studies

Journal of Chemistry, Volume 2022, Issue 1, 2022., 2022
Fungal infections, including those caused by Candida spp., are recognized in immunocompromised individuals for their high rates of morbidity and mortality. Microorganism resistance to conventional drugs compromises treatment effectiveness and yet also reveals the need to develop new drugs.
Allana B. S. Duarte, Yunierkis Perez-Castillo, Patrícia Néris Andrade, Ricardo D. de Castro, Damião P. de Sousa, Maria F. Carvalho   +5 more
wiley   +1 more source

Molecular underpinnings of methyl jasmonate‐induced resistance in Norway spruce

Plant, Cell &Environment, Volume 43, Issue 8, Page 1827-1843, August 2020., 2020
Abstract In response to various stimuli, plants acquire resistance against pests and/or pathogens. Such acquired or induced resistance allows plants to rapidly adapt to their environment. Spraying the bark of mature Norway spruce (Picea abies) trees with the phytohormone methyl jasmonate (MeJA) enhances resistance to tree‐killing bark beetles and their
Melissa H. Mageroy, Samuel W. Wilkinson, Torstein Tengs, Hugh Cross, Marit Almvik, Pierre Pétriacq, Adam Vivian‐Smith, Tao Zhao, Carl Gunnar Fossdal, Paal Krokene   +9 more
wiley   +1 more source

ModEnzA: Accurate Identification of Metabolic Enzymes Using Function Specific Profile HMMs with Optimised Discrimination Threshold and Modified Emission Probabilities

Advances in Bioinformatics, Volume 2011, Issue 1, 2011., 2011
Various enzyme identification protocols involving homology transfer by sequence‐sequence or profile‐sequence comparisons have been devised which utilise Swiss‐Prot sequences associated with EC numbers as the training set. A profile HMM constructed for a particular EC number might select sequences which perform a different enzymatic function due to the ...
Dhwani K. Desai, Soumyadeep Nandi, Prashant K. Srivastava, Andrew M. Lynn, Burkhard Morgenstern   +4 more
wiley   +1 more source

The Fox and the Rabbits—Environmental Variables and Population Genetics (1) Replication Problems in Association Studies and the Untapped Power of GWAS (2) Vitamin A Deficiency, Herpes Simplex Reactivation and Other Causes of Alzheimer′s Disease

International Scholarly Research Notices, Volume 2011, Issue 1, 2011., 2011
Classical population genetics shows that varying permutations of genes and risk factors permit or disallow the effects of causative agents, depending on circumstance. For example, genes and environment determine whether a fox kills black or white rabbits on snow or black ash covered islands.
C. J. Carter, A. Conti
wiley   +1 more source

A basidomycetous hydroxynaphthalene-prenylating enzyme exhibits promiscuity toward prenyl donors. [PDF]

Appl Microbiol Biotechnol, 2023
Martin A, Dierlamm N, Zocher G, Li SM.
europepmc   +1 more source

Prenylation of dimeric cyclo-L-Trp-L-Trp by the promiscuous cyclo-L-Trp-L-Ala prenyltransferase EchPT1. [PDF]

Appl Microbiol Biotechnol, 2023
Li W, Xie X, Liu J, Yu H, Li SM.
europepmc   +1 more source

Chemoenzymatic Late-Stage Modifications Enable Downstream Click-Mediated Fluorescent Tagging of Peptides. [PDF]

Angew Chem Int Ed Engl, 2023
Colombano A, Dalponte L, Dall'Angelo S, Clemente C, Idress M, Ghazal A, Houssen WE.   +6 more
europepmc   +1 more source

Mutation of the eunicellane synthase Bnd4 alters its product profile and expands its prenylation ability. [PDF]

Org Biomol Chem, 2022
Xu B, Ning W, Wei X, Rudolf JD.
europepmc   +1 more source

Peptide Prenylation Follows Divergent Substrate Engagement Rules. [PDF]

J Am Chem Soc
Wakeel MA, McShan AC, Agarwal V.
europepmc   +1 more source

Effects and potential mechanism of Ca²⁺/calmodulin‑dependent protein kinase II pathway inhibitor KN93 on the development of ovarian follicle. [PDF]

Int J Mol Med, 2022
Yu J, Xie X, Ma Y, Yang Y, Wang C, Xia G, Ding X, Liu X.   +7 more
europepmc   +1 more source