Results 121 to 130 of about 454 (180)
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Dimethylamine formation in man
Biochemical Pharmacology, 1993Trimethylamine N-oxide, a common food component, has been identified as a major source of urinary dimethylamine in man. The potential pathophysiological consequences of exposure to dietary derived dimethylamine are raised.
A Q, Zhang +3 more
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Clinica Chimica Acta, 1995
The urinary excretion of dimethylamine has been measured in 203 unrelated healthy volunteers (102 male) who maintained their normal diets. The results for female volunteers are the first reported in the literature. The average daily output was 17.43 +/- 11.80 mg (mean +/- S.D.) (21.21 +/- 14.78 male; 13.74 +/- 5.65 female) with values for the majority ...
A Q, Zhang, S C, Mitchell, R L, Smith
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The urinary excretion of dimethylamine has been measured in 203 unrelated healthy volunteers (102 male) who maintained their normal diets. The results for female volunteers are the first reported in the literature. The average daily output was 17.43 +/- 11.80 mg (mean +/- S.D.) (21.21 +/- 14.78 male; 13.74 +/- 5.65 female) with values for the majority ...
A Q, Zhang, S C, Mitchell, R L, Smith
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Xenobiotica, 1994
1. The fate of [14C]-dimethylamine was investigated following oral administration to four male volunteers. 2. The major route of excretion was urine, with 94% of the administered radioactivity being voided over 3 days (87% during the first 24 h). Small amounts (1-3%) of radioactivity were found in the faeces and expired air. 3.
A Q, Zhang +4 more
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1. The fate of [14C]-dimethylamine was investigated following oral administration to four male volunteers. 2. The major route of excretion was urine, with 94% of the administered radioactivity being voided over 3 days (87% during the first 24 h). Small amounts (1-3%) of radioactivity were found in the faeces and expired air. 3.
A Q, Zhang +4 more
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The origin of urinary dimethylamine
Biochimica et Biophysica Acta (BBA) - General Subjects, 1965Abstract 1. 1. Evidence is presented to show that dimethylamine is derived, partly, from ingested choline and lecithin. The formation of dimethylamine from choline is dependent on bacterial action in the intestine. 2. 2. Results of experiments with trimethylamine suggest that trimethylamine is an intermediate in the conversion of choline to ...
A M, Asatoor, M L, Simenhoff
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, 2020 The structure of dimethylamine
The Journal of Chemical Physics, 1983An r0 structure is determined for dimethylamine from earlier microwave data. With the constraint δr0(CH–CD)=δr0(NH–ND), CH bond lengths of 1.0958, 1.0981, and 1.1060 A° are obtained, in excellent agreement with earlier predictions from ‘‘isolated’’ CH stretching frequencies. The new value of r0NH of 1.011 A° is significantly shorter than the earlier rs
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Contact allergy to oleamidopropyl dimethylamine
Contact Dermatitis, 1984Contact allergy to the cationic emulfisier oleamidopropyl dimethylamine was demonstrated in 3 patients. In every case the emulsifier was present in a particular brand of body lotion. Patch test concentrations of 0.1% and 0.5% in water are proposed; slightly higher concentrations may induce irritant responses.
de Groot, A.C., Liem, Dhiam H.
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Toxicity of nitrite and dimethylamine in rats
Toxicology Letters, 1983Weanling male Wistar strain rats were administered, through the drinking water, nitrite (0.2%) and dimethylamine (DMA) (0.2%), either singly or in combination for 9 months. Some animals also received 0.5% butylated hydroxytoluene (BHT) in the diet. Nitrite, as well as DMA, caused higher in vitro lipoperoxidation, free lysosomal enzyme activities and ...
R, Darad, A K, De, A S, Aiyar
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Fate of dimethylamine in rat and mouse
Xenobiotica, 19941. [U-14C]-dimethylamine hydrochloride was administered by gavage (20 mumol/kg body weight) to adult male Wistar rat and CD1 strain mouse. 2. In both species, urine was the main route of excretion with the majority of radiolabel (91%) being voided during the first day.
A Q, Zhang, S C, Mitchell, R L, Smith
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Dimethylamine as a Substrate in Hydroaminoalkylation Reactions
Angewandte Chemie International Edition, 2017AbstractTransition‐metal‐catalyzed hydroaminoalkylations of alkenes have made great progress over the last decade and are heading to become a viable alternative to the industrial synthesis of amines through hydroformylation of alkenes and subsequent reductive amination.
Jens Bielefeld, Sven Doye
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