The search for the 'next' euphoric non-fentanil novel synthetic opioids on the illicit drugs market: current status and horizon scanning [PDF]
, 2019 Purpose: A detailed review on the chemistry and pharmacology of non-fentanil novel synthetic opioid receptor agonists, particularly N-substituted benzamides and acetamides (known colloquially as U-drugs) and 4-aminocyclohexanols, developed at the Upjohn ...
A Helander +63 more
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Annual report 2014 of the EURL-FCM on activities carried out for the implementation of Regulation (EC) no 882/2004 [PDF]
, 2015 This annual report presents the activities of the EURL FCM in 2014 under the Administrative Agreement N °SANCO 2014/FOOD SAFETY/083-Food Contact Materials" (Ref. JRC: 33483 EURL FCM IX). The work programme 2014 for the European Union Reference Laboratory
SIMONEAU Catherine
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Identification of potential inhibitors of casein kinase 2 alpha of Plasmodium falciparum with potent in vitro activity [PDF]
, 2023 Funding Information: The authors are incredibly grateful to Brazilian funding agencies Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP), CNPq, CAPES, Fundação de Apoio à Pesquisa do Estado de Goiás (FAPEG), and to the Swedish Research ...
Almeida, Vitor M. +17 more
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Electrocatalytic C─N Coupling in Aqueous Solutions for High‐Value Product Synthesis
Angewandte Chemie, EarlyView.Electrocatalytic C–N coupling offers a sustainable route to synthesize crucial organic nitrogen compounds from abundant feedstocks under mild conditions. This review examines recent progress in overcoming key challenges, like slow kinetics and competing reactions through advanced catalysts and novel mechanisms, paving the way for transforming chemical ...
Yunpeng Zuo +3 more
wiley +2 more sources
Endogenous formation of dimethylamine [PDF]
Biochemical Journal, 1985 An understanding of the biosynthesis and metabolism of dimethylamine (DMA) is important because it is a precursor of dimethylnitrosamine (nitroso-DMA). DMA is the major short-chain aliphatic amine in human and rat urine. DMA is formed from trimethylamine (TMA), which, in turn, is a breakdown product of dietary choline.
S H, Zeisel, K A, DaCosta, J G, Fox
openaire +2 more sources
Regiodivergent C3 and C4 Amination of Quinolines via Radical and Ionic Pathways
Angewandte Chemie, EarlyView.A regiodivergent strategy converts a single N‐aminoquinolinium precursor into either C3‐ or C4‐aminated quinolines. Nucleophile‐induced dearomatization diverges into light‐driven N‐centered radical capture (C3) or base‐promoted SNAr (C4), enabling rapid assembly of aminoquinoline libraries and late‐stage diversification.
Ye‐Eun Kim +3 more
wiley +2 more sources
Method Development for the Assignment of NMR Peaks and the Determination of Quaternary Protein Structure using Reductive Methylation [PDF]
, 2015 The work described herein is centered on reductive methylation, a chemical modification reaction, which allows for the introduction of methyl groups at the primary amines of the lysine side chain and at the N-terminus.
Brady, Pamlea Nicole
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Heterogeneous PdAg alloy catalyst for selective methylation of aromatic amines with formic acid under an additive-free and solvothermal one-pot condition [PDF]
The methylation of amines for the synthesis of methylamines and dimethylamines as platform chemicals has been attempted mostly by homogeneous catalysts with acid additives.
Hwang, YH, Kim, DP, Singh, AK
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Activated carbons as green and effective catalysts for generation of reactive radicals in degradation of aqueous phenol [PDF]
, 2013 Several activated carbons (ACs) were used as metal-free catalysts for degradation of a toxic organiccompound, phenol, in the presence of different oxidants, H2O2, peroxydisulfate (PS) and peroxymonosulfate (PMS).
Muhammad, Syaifullah +3 more
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Multivalent bacteria binding by flexible polycationic microsheets matching their surface charge density [PDF]
, 2020 Aiming at the overall negative surface charge of bacteria, a new strategy of antibacterial agents based on large polymer‐modified graphene oxide (GO) sheets is assessed. The presented flexible, polycationic sheets match the size and charge density of the
Ahmed, Rameez +8 more
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