Results 101 to 110 of about 94,396 (311)

Clinical, laboratory and histopathologica investigation of the protective effect of dimethylsulfoxide (dmso) on experimentally induced various types of intestinal strangulation obstruction in dogs [PDF]

Eurasian Journal of Veterinary Sciences
The aim of this study ıs lo evaluate the protective effect of dimethylsulfoxide (DMSO), a scavenger of hydroxyl radical, on the experimentally induced ischemia reperfusion injury by two different intestinal strangulation obstruction in dogs.
Cengiz Ceylan, Yılmaz Koç
doaj  

1-((E)-{2-[4-(2-{(1E)-[(carbamothioylamino)imino]methyl}phenoxy)butoxy]benzylidene}amino)thiourea dimethyl sulfoxide disolvate

IUCrData, 2016
The title compound, C20H24N6O2S2·2C2H6OS, has crystallographically imposed centrosymmetry. The packing is assisted by N—H...O, C—H...O and N—H...S interactions with the lattice solvent molecules, forming a two-dimensional network parallel to (1-10).
Joel T. Mague, Shaaban K. Mohamed, Mehmet Akkurt, Eman M. M. Abdel-Raheem, Mustafa R. Albayati   +4 more
doaj   +1 more source

New Hydrazone Derivatives Featuring Isatin and Piperazine Moieties: Synthesis, Cytotoxicity Evaluation, and Molecular Modeling Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT In this study, ten novel compounds (IPH1–IPH10) were designed by integrating three pharmacophores (isatin, piperazine, and hydrazone) commonly found in the molecular structures of anticancer agents. The target molecules were obtained by the reaction of in‐house prepared 4‐(4‐(pyridin/pyrimidin‐2‐yl)piperazin‐1‐yl)benzohydrazide with various ...
Semiha Köprü, Münevver Baran, Miyase Gözde Gündüz, Şengül Dilem Doğan   +3 more
wiley   +1 more source

Antihypertensive effects of new dihydropyridine derivatives on phenylephrine-raised blood pressure in rats

Research in Pharmaceutical Sciences, 2016
Changes in the substitutions at C-3 and C-5 positions of 4-(1-methyl-5-nitro-2-imidazolyl) dihydropyridine analogs of nifedipine have led to changes in potency of the compounds. The objective of the present study was to examine the hypotensive effects of
Sara Rowghani Haghighi Fard, Ramin Miri, Ali Akbar Nekooeian   +2 more
doaj   +1 more source

Resveratrol given intraperitoneally does not inhibit the growth of high-risk t(4;11) acute lymphoblastic leukemia cells in a NOD/SCID mouse model. [PDF]

, 2011
The efficacy of resveratrol as a preventive agent against the growth of t(4;11) acute lymphoblastic leukemia (ALL) was evaluated in NOD.CB17-Prkdcscid/J mice engrafted with the human t(4;11) ALL SEM cell line.
Ducore, Jonathan M, Keen, Carl L, Newman, John W, Pedersen, Theresa L, Storms, David H, Zunino, Susan J   +5 more
core   +1 more source

Dimethylsulfoxide attenuates ischemia-reperfusion injury in rat testis.

Acta Cirurgica Brasileira, 2010
PURPOSE To evaluate the protective role of dimethylsulfoxide (DMSO) in a rat model of testis ischemia/reperfusion (I/R). METHODS Twenty-four male Wistar rats were randomized in two equal groups.
S. Guimarães, O. Kimura, P. R. L. Vasconcelos   +2 more
semanticscholar   +1 more source

Large‐Scale Evaluation of Traditional Chinese Medicines Reveals Potential PPARγ Modulators for Type 2 Diabetes Management

Journal of Clinical Laboratory Analysis, EarlyView.
Identifying novel treatments for diabetic management is always a competitive research topic all over the world. PPAR‐γ is one of the key regulators involved in glucose and lipid metabolism and improves insulin sensitivity and glucose homeostasis. This study investigated the impacts of 639 traditional Chinese medicine (TCM) on PPAR‐γ gene promoter ...
Mingyuan Dou, Shandra Jones, Juan Montes, Jonathan Ritter, Li‐Yu Shih, Chia‐Jung Chan, Ying‐Chou Lin, Min Chen, Shih‐Yin Chen, Ning Wu   +9 more
wiley   +1 more source

Cryopreservation of human mucosal tissues.

PLoS ONE, 2018
BackgroundCryopreservation of leukocytes isolated from the cervicovaginal and colorectal mucosa is useful for the study of cellular immunity (see Hughes SM et al. PLOS ONE 2016).
Sean M Hughes, April L Ferre, Sarah E Yandura, Cory Shetler, Chris A R Baker, Fernanda Calienes, Claire N Levy, Rena D Astronomo, Zhiquan Shu, Gretchen M Lentz, Michael Fialkow, Anna C Kirby, M Juliana McElrath, Elizabeth Sinclair, Lisa C Rohan, Peter L Anderson, Barbara L Shacklett, Charlene S Dezzutti, Dayong Gao, Florian Hladik   +19 more
doaj   +1 more source

Innovative γ‐Oryzanol and KC2 Based Lipid Nanoparticles: OryKL Platform Provides Safe and Efficient In Vivo mRNA Delivery

Small, EarlyView.
Identified through multi‐stage selection process, a formulation combining γ‐oryzanol and DLin‐KC2‐DMA, termed as OryKL, demonstrates unique nano‐structural features, highly efficient mRNA transfection and functional integrity during long‐term storage, enables broad biodistribution and distinct cell tropism following intravenous administration with no ...
Pengkai Shi, Haikun Liu, Ahmed Refaat, Hung Nguyen, Anne Nguyen, Kaiting Miao, Yuyang Song, Sylvain Trépout, Rico F. Tabor, Liliana de Campo, Karlheinz Peter, Mark Louis P. Vidallon, Xiaowei Wang   +12 more
wiley   +1 more source

The crystal structure of 3-(1H-benzo[d]imidazol-2-yl)-7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydroquinolin — dimethylsulfoxide (1/1), C21H19ClFN3O2S

Zeitschrift für Kristallographie - New Crystal Structures, 2019
C21H19ClFN3O2S, monoclinic, P21/n (no. 14), a = 10.1495(4) Å, b = 8.9769(5) Å, c = 22.1431(10) Å, β = 99.901(4)°, V = 1987.43(16) Å3, Z = 4, Rgt(F) = 0.0473, wRref(F2) = 0.1418, T = 293(2) K.
Rasras Anas J., Sinnokrot Mutasem, AlDamen Murad A., Khanfar Monther A., Al-Qawasmeh Raed A.   +4 more
doaj   +1 more source