Results 161 to 170 of about 43,558 (267)

Oxygen‐independent expression of HIF‐1α during the cell cycle in hepatocellular carcinoma cells controls essential metabolic pathways under normoxia

open access: yesThe FEBS Journal, Volume 293, Issue 11, Page 3140-3165, June 2026.
Intra‐tumoral oxygen deprivation (hypoxia) promotes the activation of hypoxia‐inducible factors (HIFs) that orchestrate the transcriptional adaptation of cancer cells to hypoxia. Hypoxia is prevalent in hepatocellular carcinoma (HCC), a cancer type with limited therapeutic options.
Ioanna‐Maria Gkotinakou   +6 more
wiley   +1 more source

The Skin and Oral Hydration Benefits of Caryophyllene Through Aquaporins 3 and 5 Type Modulation in Keratinocytes: in silico and in Vitro Research

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Objective Skin xerosis and xerostomia are partially associated with decreased expression and molecular activity of aquaporins 3 and 5 types (AQP3 and AQP5) in skin epidermal cells. While cosmetic occlusive agents and emollients are effective in improving symptoms of skin dryness, maintaining intensive water transport and physiological ...
Alina Yarovaya   +5 more
wiley   +1 more source

Assessing D‐Squame as a Minimally Invasive Technique to Evaluate the Cutaneous Immune Response mRNA in a Dog Model of Canine Atopic Dermatitis

open access: yesVeterinary Dermatology, Volume 37, Issue 3, Page 353-364, June 2026.
ABSTRACT Background Canine atopic dermatitis (cAD) is a multifactorial, inherited skin disease, estimated to affect ≤ 15% of dogs. Studies of skin messenger mRNA in cAD currently use invasive methods, including blood sampling and biopsy collection, whilst advances in human atopic dermatitis study methodology have demonstrated reliable use of minimally ...
Xavier Langon   +5 more
wiley   +1 more source

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