Intra‐tumoral oxygen deprivation (hypoxia) promotes the activation of hypoxia‐inducible factors (HIFs) that orchestrate the transcriptional adaptation of cancer cells to hypoxia. Hypoxia is prevalent in hepatocellular carcinoma (HCC), a cancer type with limited therapeutic options.
Ioanna‐Maria Gkotinakou +6 more
wiley +1 more source
ABSTRACT Objective Skin xerosis and xerostomia are partially associated with decreased expression and molecular activity of aquaporins 3 and 5 types (AQP3 and AQP5) in skin epidermal cells. While cosmetic occlusive agents and emollients are effective in improving symptoms of skin dryness, maintaining intensive water transport and physiological ...
Alina Yarovaya +5 more
wiley +1 more source
Nuclear quantum effects and vibrational resonances in organic hydrates: theoretical and experimental insights from DMSO monohydrate. [PDF]
Botti G, Mandelli G.
europepmc +1 more source
Protein structure and coupled solvent dynamics in α-synuclein fibrils under controlled confinement. [PDF]
Whitcomb KL, Warncke K.
europepmc +1 more source
ABSTRACT Background Canine atopic dermatitis (cAD) is a multifactorial, inherited skin disease, estimated to affect ≤ 15% of dogs. Studies of skin messenger mRNA in cAD currently use invasive methods, including blood sampling and biopsy collection, whilst advances in human atopic dermatitis study methodology have demonstrated reliable use of minimally ...
Xavier Langon +5 more
wiley +1 more source
Annual Banned-Substance Review 18th Edition-Analytical Approaches in Human Sports Drug Testing 2024/2025. [PDF]
Thevis M, Kuuranne T, Geyer H.
europepmc +1 more source
Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium. [PDF]
Yamashita TR, Usuki T, Kay RR, Saito T.
europepmc +1 more source
Down-regulation of Shh in the hair follicles of mice during chemotherapy-induced hair loss is mediated by the JAK/STAT1 signaling pathway. [PDF]
Fan R +6 more
europepmc +1 more source
Elevated 5-HTR7 deteriorates dysregulated megakaryocytopoiesis in immune thrombocytopenic purpura via upregulating the PKA/Orai1/ERK1/2 pathway. [PDF]
Zhou M +8 more
europepmc +1 more source
Analytical Method by Headspace-Gas Chromatography for Determination of Six Residual Solvents in Losartan Potassium Raw Material. [PDF]
de Camargo VB, Garcia CV.
europepmc +1 more source

