Results 151 to 160 of about 94,396 (311)
It may seem counterintuitive to first target a ruthenium alkylidyne when Grubbs‐type ruthenium carbene complexes are the actual goal. In the end, however, this tactic pays valuable dividends in terms of practicality, atom economy, flexibility as well as safety: the new route provides ready access to a large assortment of catalysts for alkene metathesis
Mingxu Cui, Alois Fürstner
wiley +2 more sources
Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function
Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng +8 more
wiley +1 more source
Summary Plants and soils have been moved around the world for centuries, but invasive mushrooms receive scant attention. The Amanita muscaria species complex was introduced to South Africa in the context of forestry, but its origins, ecology and recent evolution are unstudied. We sequenced the genomes of 24 Northern and Southern Hemisphere A. muscaria,
Grant R. Nickles +39 more
wiley +1 more source
Novel polyhydroxylated bis‐chalcones were successfully synthesized and demonstrated COX‐2 selective inhibition. The most potent and selective inhibitor exhibited a mixed‐type inhibition mechanism with COX‐2. Its additional bulk preferentially blocked the access to the active pocket of COX‐1 rather than COX‐2. Selective inhibition of COX‐2 is considered
Rui Pereira +7 more
wiley +1 more source
Recent Developments in Sustainable Solubilization
We highlight several recent developments in sustainable solubilization. Particular attention is given to the use of bio‐based solvents derived from renewable resources, the strategic use of water as a solvent, and alternative, sustainable solubilizers such as hydrotropes.
Eva Müller, Werner Kunz
wiley +1 more source
Fluorine‐free acesulfame‐based ionic liquids and salts were synthesized and comprehensively analysed, revealing how anionic structure governs key physicochemical properties, paving the way towards safer and more sustainable electrolytes for clean energy storage.
Wern Huay Mah +3 more
wiley +1 more source
Research and development of a capacity nonaqueous secondary battery Fourth quarterly report, Jul. - Sep. 1965 [PDF]
High capacity nonaqueous secondary battery development - lithium deposition and cycling, ionic solvation, cathode construction and discharge efficiency, and solvent ...
Hill, K. R., Rao, M. L. B., Selim, R. G.
core +1 more source
Influence of dimethylsulfoxide on RNA structure and ligand binding.
Janghyun Lee +3 more
semanticscholar +1 more source
The helminth TGF‐β mimic TGM4 activates SMAD signaling in macrophages and T cells through canonical TGF‐β receptors and the CD44 co‐receptor, through Domains 1–5 (D1‐5). In fibroblasts, which express lower levels of CD44, TGM4 binds but does not transduce a signal; furthermore, it inhibits activation by agonist ligands such as TGF‐β itself, in a manner
Kyle T. Cunningham +15 more
wiley +1 more source
Nuclear quantum effects and vibrational resonances in organic hydrates: theoretical and experimental insights from DMSO monohydrate. [PDF]
Botti G, Mandelli G.
europepmc +1 more source

