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Melanin pigments are substances produced by a broad variety of pathogenic microorganisms, including bacteria, fungi, and helminths. Microbes predominantly produce melanin pigment via tyrosinases, laccases, catecholases, and the polyketide synthase ...
CARLOS P Taborda +2 more
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The monosaccharide N-acetylglucosamine (GlcNAc) is a major component of microbial cell walls and is ubiquitous in the environment. GlcNAc stimulates developmental pathways in the fungal pathogen Candida albicans, which is a commensal organism that ...
Sarah A Gilmore +2 more
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Molecular biology of the dimorphic fungi Paracoccidioides spp [PDF]
Abstract Paracoccidioides spp, herein commonly referred as Paracoccidioides brasiliensis, is the etiological agent of paracoccidioidomycosis (PCM), the most prevalent systemic mycosis endemic in Latin America. Many aspects of the biology of P. brasiliensis remain unknown, in particular its ecology and the apparent lack of a sexual reproduction stage ...
Mark H J Sturme +2 more
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Current Microbiology, 1979
The polyamine contents of the yeast and mycelial forms of seven dimorphic fungi were examined to determine if a relationship existed between polyamine composition and fungal morphology. Although the polyamine contents differed, no consistent patterns emerged.
Michael Marshall +3 more
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The polyamine contents of the yeast and mycelial forms of seven dimorphic fungi were examined to determine if a relationship existed between polyamine composition and fungal morphology. Although the polyamine contents differed, no consistent patterns emerged.
Michael Marshall +3 more
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Global Control of Dimorphism and Virulence in Fungi
Science, 2006Microbial pathogens that normally inhabit our environment can adapt to thrive inside mammalian hosts. There are six dimorphic fungi that cause disease worldwide, which switch from nonpathogenic molds in soil to pathogenic yeast after spores are inhaled and exposed to elevated temperature. Mechanisms that regulate this switch remain obscure.
Julie C, Nemecek +2 more
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Defining Virulence Genes in the Dimorphic Fungi
Annual Review of Microbiology, 2006Most dimorphic fungal pathogens cause respiratory disease in mammals and must therefore possess virulence mechanisms to combat and overcome host pulmonary defenses. Over the past decade, advances in genetic tools have made it possible to investigate the basis of dimorphic fungal pathogenesis at the molecular level. Gene disruptions and RNA interference
Chad A, Rappleye, William E, Goldman
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