Unraveling the dynamic transcriptomic changes during the dimorphic transition of Talaromyces marneffei through time-course analysis [PDF]
IntroductionSystemic dimorphic fungi pose a significant public health challenge, causing over one million new infections annually. The dimorphic transition between saprophytic mycelia and pathogenic yeasts is strongly associated with the pathogenesis of ...
Minghao Du +7 more
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MADS-Box Transcription Factor MadsA Regulates Dimorphic Transition, Conidiation, and Germination of Talaromyces marneffei [PDF]
The opportunistic human pathogen Talaromyces marneffei exhibits a temperature-dependent dimorphic transition, which is closely related with its pathogenicity.
Qiangyi Wang +12 more
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Cloning and disruption of the UeArginase in Ustilago esculenta: evidence for a role of arginine in its dimorphic transition [PDF]
Background Ustilago esculenta, a typical dimorphic fungus could infect Zizania latifolia and induce host stem swollen to form an edible vegetable called Jiaobai in China.
Yafen Zhang +8 more
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Knockdown of Thitarodes host genes influences dimorphic transition of Ophiocordyceps sinensis in the host hemolymph [PDF]
The Chinese cordyceps, a unique parasitic complex of Thitarodes/Hepialus ghost moths and Ophiocordyceps sinensis fungus in the Tibetan Plateau, is a highly valuable biological resource for medicine and health foods in Asian countries.
Tanqi Sun +11 more
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GATA‐type transcription factor MrNsdD regulates dimorphic transition, conidiation, virulence and microsclerotium formation in the entomopathogenic fungus Metarhizium rileyi [PDF]
Summary The GATA‐type sexual development transcription factor NsdD has been implicated in virulence, secondary metabolism and asexual development in filamentous fungi.
Caiyan Xin +5 more
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Signature gene expression reveals novel clues to the molecular mechanisms of dimorphic transition in Penicillium marneffei. [PDF]
Systemic dimorphic fungi cause more than one million new infections each year, ranking them among the significant public health challenges currently encountered. Penicillium marneffei is a systemic dimorphic fungus endemic to Southeast Asia.
Ence Yang +7 more
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Functional diversification of the MADS-box gene family in fine-tuning the dimorphic transition of Talaromyces marneffei [PDF]
The dynamic transition between yeast and hypha is a crucial adaptive mechanism for many human pathogenic fungi, including Talaromyces marneffei, a thermodimorphic fungus responsible for causing fatal talaromycosis. In the current study, we elucidated the
Xueyan Hu +6 more
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The yeast-to-filament transition is an important cellular response to environmental stimulations in dimorphic fungi. In addition to activators, there are repressors in the cells to prevent filament formation, which is important to keep the cells in the ...
Jia-Wen Chen +3 more
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Glucosamine stimulates pheromone-independent dimorphic transition in Cryptococcus neoformans by promoting Crz1 nuclear translocation. [PDF]
Morphotype switch is a cellular response to external and internal cues. The Cryptococcus neoformans species complex can undergo morphological transitions between the yeast and the hypha form, and such morphological changes profoundly affect cryptococcal ...
Xinping Xu +6 more
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Coordinated gene family evolution shapes the genome of dimorphic Mucorales [PDF]
Dimorphic organisms possess the remarkable genome capacity to alternate genetic information between two distinct life forms. In dimorphic Mucorales, lineages can reversibly transition between yeast and mycelium as a function of environmental stimuli ...
Ghizlane Tahiri +7 more
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