Results 11 to 20 of about 8,625 (192)

Calcineurin plays key roles in the dimorphic transition and virulence of the human pathogenic zygomycete Mucor circinelloides. [PDF]

PLoS Pathogens, 2013
Many pathogenic fungi are dimorphic and switch between yeast and filamentous states. This switch alters host-microbe interactions and is critical for pathogenicity.
Soo Chan Lee, Alicia Li, Silvia Calo, Joseph Heitman   +3 more
doaj   +2 more sources

YlAaf1-YlAaf2, a bipartite SANT domain-containing complex of transcriptional activator, promotes filamentous growth in the dimorphic yeast Yarrowia lipolytica [PDF]

mSphere
The yeast-to-filament transition is important for dimorphic fungi to adapt to different environmental conditions. Transcriptional activators that activate downstream target genes in response to environmental stimulations are particularly important for ...
Meng-Yang Xu, Zhen-Hua Wang, Xiang-Dong Gao   +2 more
doaj   +2 more sources

Species-specific circular RNA circDS-1 enhances adaptive evolution in Talaromyces marneffei through regulation of dimorphic transition. [PDF]

PLoS Genetics
Thermal adaptability is a crucial characteristic for mammalian pathogenic fungi that originally inhabit natural ecosystems. Thermally dimorphic fungi have evolved a unique ability to respond to host body temperature by shifting from mycelia to yeast. The
Xueyan Hu, Minghao Du, Changyu Tao, Juan Wang, Yun Zhang, Yueqi Jin, Ence Yang   +6 more
doaj   +2 more sources

BrlA and AbaA Govern Virulence-Required Dimorphic Switch, Conidiation, and Pathogenicity in a Fungal Insect Pathogen

mSystems, 2019
Dimorphic plant and human mycopathogens require a switch from the usual yeast growth to filamentous growth for host tissue penetration, and the switch is controlled by multiple signaling systems other than the central developmental pathway.
An-Xue Zhang, Amina-Zahra Mouhoumed, Sen-Miao Tong, Sheng-Hua Ying, Ming-Guang Feng   +4 more
doaj   +3 more sources

Juvenile hormone regulates the maturation of sexually dimorphic naive ethanol olfactory preference in Drosophila melanogaster [PDF]

Royal Society Open Science
The molecular mechanisms underlying the maturation of innate reward behaviours remain poorly understood. We have identified a sexually dimorphic innate reward behaviour in Drosophila melanogaster that varies depending on the age, sex and mating status in
Antonio Marini-Davis, Ryan Oliver, Bailey Godwin, Sera Chase, Ziam Khan, Fernando J. Vonhoff   +5 more
doaj   +2 more sources

Signaling Pathways Regulating Dimorphism in Medically Relevant Fungal Species [PDF]

Pathogens
Pathogenic fungi that exhibit the ability to alternate between hyphal and yeast morphology in response to environmental stimuli are considered dimorphic. Under saprobic conditions, some fungi exist as filamentous hyphae, producing conidia.
Uriel Ramírez-Sotelo, Manuela Gómez-Gaviria, Héctor M. Mora-Montes   +2 more
doaj   +2 more sources

Copper Ion Mediates Yeast-to-Hypha Transition in Yarrowia lipolytica

Journal of Fungi, 2023
Copper is an essential element that maintains yeast physiological function at low concentrations, but is toxic in excess. This study reported that Cu(II) significantly promoted the yeast-to-hypha transition of Yarrowia lipolytica in dose-dependent manner.
Mengqu Ran, Guowei Zhao, Liangcheng Jiao, Zhaorui Gu, Kaixin Yang, Lishuang Wang, Xinghong Cao, Li Xu, Jinyong Yan, Yunjun Yan, Shangxian Xie, Min Yang   +11 more
doaj   +1 more source

Chemical Profile, Anti-Microbial and Anti-Inflammaging Activities of Santolina rosmarinifolia L. Essential Oil from Portugal

Antibiotics, 2023
Fungal infections and the accompanying inflammatory responses are associated with great morbidity and mortality due to the frequent relapses triggered by an increased resistance to antifungal agents.
Jorge M. Alves-Silva, Maria José Gonçalves, Ana Silva, Carlos Cavaleiro, Maria Teresa Cruz, Lígia Salgueiro   +5 more
doaj   +1 more source

Investigating the Smuts: Common Cues, Signaling Pathways, and the Role of MAT in Dimorphic Switching and Pathogenesis

Journal of Fungi, 2020
The corn smut fungus Ustilago maydis serves as a model species for studying fungal dimorphism and its role in phytopathogenic development. The pathogen has two growth phases: a saprobic yeast phase and a pathogenic filamentous phase. Dimorphic transition
Teeratas Kijpornyongpan, M. Catherine Aime   +1 more
doaj   +1 more source

Mutation in yl-HOG1 represses the filament-to-yeast transition in the dimorphic yeast Yarrowia lipolytica

Microbial Cell Factories, 2023
Background Yarrowia lipolytica is a dimorphic fungus, which switches from yeast to filament form in response to environmental conditions. For industrial purposes it is important to lock cells in the yeast or filamentous form depending on the fermentation
Dorota A. Rzechonek, Mateusz Szczepańczyk, Aleksandra M. Mirończuk   +2 more
doaj   +1 more source