Results 31 to 40 of about 1,419 (162)

The Four Critical Priority Fungi According to the World Health Organization and the Hope for New Therapies: A Focus on Cell Wall Antifungal Targets

Journal of Fungi
In 2022, the World Health Organization (WHO) released a list of four fungi identified as the most medically important global pathogens, resulting in Cryptococcus neoformans, Candidozyma auris (formerly Candida auris), Aspergillus fumigatus and Candida ...
Gabriel Davi Marena, Gabriela Corrêa Carvalho, Martha Helena Chaves Magalhães, Julia Marcondes Figueiredo, Danilo Henrique Ramos, Joshua D. Nosanchuk, Carlos Pelleschi Taborda   +6 more
doaj   +1 more source

Emergomycosis, an Emerging Thermally Dimorphic Fungal Infection: A Systematic Review

Journal of Fungi, 2023
Emergomycosis is an endemic mycosis caused by the Emergomyces species. Infections due to this agent have been reported globally. Hence, the present systematic review on Emergomyces infections was conducted to study the disease epidemiology, underlying ...
Kalaiselvi Vinayagamoorthy, Dinesh Reddy Gangavaram, Anna Skiada, Hariprasath Prakash   +3 more
doaj   +1 more source

BrlA and AbaA Govern Virulence-Required Dimorphic Switch, Conidiation, and Pathogenicity in a Fungal Insect Pathogen

mSystems, 2019
Dimorphic plant and human mycopathogens require a switch from the usual yeast growth to filamentous growth for host tissue penetration, and the switch is controlled by multiple signaling systems other than the central developmental pathway.
An-Xue Zhang, Amina-Zahra Mouhoumed, Sen-Miao Tong, Sheng-Hua Ying, Ming-Guang Feng   +4 more
doaj   +1 more source

Multiscale spectroscopic analysis of lipids in dimorphic and oleaginous Mucor circinelloides accommodate sustainable targeted lipid production

Fungal Biology and Biotechnology, 2023
Background Oleaginous fungi have versatile metabolism and able to transform a wide range of substrates into lipids, accounting up to 20–70% of their total cell mass.
V. Shapaval, A. Deniset-Besseau, D. Dubava, S. Dzurendova, J. Heitmann Solheim, A. Kohler   +5 more
doaj   +1 more source

Immunoproteomic and Immunopeptidomic Analyses of Histoplasma capsulatum Reveal Promiscuous and Conserved Epitopes Among Fungi With Vaccine Potential

Frontiers in Immunology, 2021
As there are more than 6 million human deaths due to mycoses each year, there is an urgent need to develop fungal vaccines. Moreover, given the similarities among pathogenic fungi, it may be possible to create a multi-fungi vaccine.
Brenda Kischkel, Camila Boniche-Alfaro, Isabela de Godoy Menezes, Suelen Andreia Rossi, Suelen Andreia Rossi, Claudia Blanes Angeli, Sandro Rogério de Almeida, Giuseppe Palmisano, Leila Lopes-Bezerra, Joshua D. Nosanchuk, Joshua D. Nosanchuk, Carlos Pelleschi Taborda, Carlos Pelleschi Taborda   +12 more
doaj   +1 more source

Unraveling the dynamic transcriptomic changes during the dimorphic transition of Talaromyces marneffei through time-course analysis

Frontiers in Microbiology
IntroductionSystemic dimorphic fungi pose a significant public health challenge, causing over one million new infections annually. The dimorphic transition between saprophytic mycelia and pathogenic yeasts is strongly associated with the pathogenesis of ...
Minghao Du, Changyu Tao, Xueyan Hu, Yun Zhang, Jun Kan, Juan Wang, Ence Yang, Ence Yang   +7 more
doaj   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

A roadmap to key traits of invasive Drosophilidae

Biological Reviews, EarlyView.
ABSTRACT Biological invasions have intensified in recent decades, mostly driven by international trade and travel, raising significant concerns, particularly regarding insect pests. Once non‐native species establish, they can disrupt natural ecosystem stability, undermine agroecosystem sustainability and cause substantial economic losses.
Gwenaëlle Deconninck, Bréa Raynaud‐Berton, Méghan Boulembert, Olivier Chabrerie, Aude Couty, Franck Dedeine, Patrice Eslin, Vincent Foray, Romain Georges, Patricia Gibert, Laurence Mouton, Sylvain Pincebourde, David Renault, Christelle Suppo, Hervé Colinet   +14 more
wiley   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

A TCR Transgenic Mouse Reactive with Multiple Systemic Dimorphic Fungi

, 2011
Dimorphic fungi collectively account for 5–10 million new infections annually worldwide. Ongoing efforts seek to clarify mechanisms of cellular resistance to these agents and develop vaccines.
Kevin J. Galles, Bruce S. Klein, Garry T. Cole, Chiung Yu Hung, John C. Pick-Jacobs, Marcel Wüthrich, Ben H. Gern, Hanna I. Filutowicz   +7 more
core   +1 more source