KRAS mutation: from undruggable to druggable in cancer
Signal Transduction and Targeted Therapy, 2021Liwu Fu
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Metabolic networks in mutant KRAS-driven tumours: tissue specificities and the microenvironment
Nature Reviews Cancer, 2021Samuel Andrew Kerk +2 more
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Rapid non-uniform adaptation to conformation-specific KRAS(G12C) inhibition
Nature, 2020Jenny Y Xue, Yulei Zhao, Dongsung Kim
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The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer
Nature Genetics, 2021Arafath K Najumudeen +2 more
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Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
Nature, 2017Sushrut Kamerkar +2 more
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Direct small-molecule inhibitors of KRAS: from structural insights to mechanism-based design
Nature Reviews Drug Discovery, 2016Kevan M Shokat
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KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma
Nature Reviews Cancer, 2010Sam C Wang, Matthias Hebrok
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Targeting the MAPK Pathway in KRAS-Driven Tumors
Cancer Cell, 2020Matthias Drosten, Mariano Barbacid
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Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase
Nature Medicine, 2018Dietrich A Ruess +2 more
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Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes
Nature, 2018Thomas Engleitner +2 more
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