Safety and Efficacy of Misoprostol and Dinoprostone as Cervical Ripening Agents
INTRODUCTION: The study compares safety and efficacy of misoprostol and dinoprostone as cervical ripening agents. METHODS: Patients with term, vertex, singleton pregnancy and Bishop score of 4 or less were randomly assigned to receive misoprostol ...
R Shakya, J Shrestha, P Thapa
doaj +2 more sources
Maternal serum progesterone, estradiol and estriol levels in successful dinoprostone-induced labor [PDF]
Hormone-mediated quiescence involves the maintenance of a decreased inflammatory responsiveness. However, no study has investigated whether labor induction with prostanoids is associated with changes in the levels of maternal serum hormones.
C.K. Konopka +6 more
doaj +2 more sources
Introduction Labor induction exhibits considerable variations in protocols and medication regimens. Limited studies compare vaginal dinoprostone inserts with different oral misoprostol dosages, considering parity influence.
Damaris Erhardt +3 more
doaj +2 more sources
OBJETIVO: verificar a eficácia e a segurança de dinoprostone e misoprostol para indução do parto vaginal, com ou sem o uso de ocitocina em nulíparas. MÉTODOS: realizou-se estudo retrospectivo, observacional, envolvendo 238 pacientes que foram submetidas ...
Tenilson Amaral Oliveira +3 more
doaj +2 more sources
COMPARISON OF DINOPROSTONE PLUS OXYTOCIN AND OXYTOCIN ALONE FOR INDUCTION OF LABOR [PDF]
Role of labor induction has increased in the last decade due to the early detection of fetal jeopardy. Although very useful, oxytocin alone is not always successful for induction of labor.
M. Valadan +3 more
doaj +2 more sources
Oral Misoprostol Versus Vaginal Dinoprostone for Labor Induction: A Systematic Review and Meta-Analysis. [PDF]
ABSTRACT Aim Pharmacologic cervical ripening is frequently used for labor induction, yet the comparative effectiveness, safety, and resource utilization of available agents remain uncertain. This review compared oral misoprostol with vaginal dinoprostone for labor induction in singleton pregnancies at ≥ 34 weeks' gestation.
Yeretsian T +6 more
europepmc +2 more sources
Delivery Outcomes in the First 3 Years Following the Clinical Introduction of the Dinoprostone Vaginal Insert in Japan. [PDF]
ABSTRACT Objective To evaluate utilization patterns, safety, and delivery outcomes associated with the recently introduced dinoprostone vaginal insert in Japan using multicenter real‐world data. Methods This two‐stage nationwide survey targeted training institutions certified by the Japan Society of Obstetrics and Gynecology.
Nakajima K +8 more
europepmc +2 more sources
Induction of labor after one previous cesarean: Time for the MIBAC trial. [PDF]
Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 9, Page 1644-1645, September 2026.
Brismar Wendel S, Wallström T.
europepmc +2 more sources
A randomized trial of synthetic osmotic cervical dilator for induction of labor vs dinoprostone vaginal insert [PDF]
Background: Induction of labor is a commonly performed obstetric intervention. Vaginal prostaglandin E2 (dinoprostone) is a first-choice agent. Mechanical methods of induction are slower to achieve cervical ripening but have a lower risk of adverse ...
Hardy, Pollyanna +5 more
core +3 more sources
Oral misoprostol (PGE1) vs vaginal dinoprostone (PGE2) for labor induction: individual participant data meta-analysis of randomized controlled trials. [PDF]
ABSTRACT Objective To compare the effectiveness and safety of oral misoprostol vs vaginal dinoprostone for the induction of labor (IOL) using an individual participant data (IPD) meta‐analysis. Methods We used a Cochrane review and searched Ovid MEDLINE, Ovid Embase, Ovid Emcare, CINAHL Plus, Scopus and ClinicalTrials.gov to identify randomized ...
Tan SY +13 more
europepmc +2 more sources

