Results 41 to 50 of about 327 (157)

The potent anti-cancer activity of Dioclea lasiocarpa lectin [PDF]

Journal of Inorganic Biochemistry, 2017
The lectin DLasiL was isolated from seeds of the Dioclea lasiocarpa collected from the northeast coast of Brazil and characterized for the first time by mass spectrometry, DNA sequencing, inductively coupled plasma-mass spectrometry, electron paramagnetic resonance, and fluorescence spectroscopy.
Ana C.S. Gondim, Isolda Romero-Canelón, Eduardo H.S. Sousa, Claudia A. Blindauer, Jennifer S. Butler, María J. Romero, Carlos Sanchez-Cano, Bruno L. Sousa, Renata P. Chaves, Celso S. Nagano, Benildo S. Cavada, Peter J. Sadler   +11 more
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Crystal structure of Dioclea violacea lectin and a comparative study of vasorelaxant properties with Dioclea rostrata lectin

The International Journal of Biochemistry & Cell Biology, 2013
Lectins from Diocleinae subtribe belong to the family of legume lectins and are characterized by high identity between their amino acids sequences. It has been shown that punctual differences in amino acid sequences, such as one single amino acid or an alternative conformation, represent changes in biological activities caused by these lectins ...
Bezerra, Maria Júlia Barbosa, Rodrigues, Natália Velloso Fontenelle Camelo, Pires, Alana de Freitas, Bezerra, Gustavo Arruda, Nobre, Camila Bezerra, Alencar, Kássia Lys de Lima, Soares, Pedro Marcos Gomes, Nascimento, Kyria Santiago do, Nagano, Celso Shiniti, Martins, Jorge Luiz, Gruber, Karl, Sampaio, Alexandre Holanda, Delatorre, Plinio, Rocha, Bruno Anderson Matias, Assreuy, Ana Maria Sampaio, Cavada, Benildo Sousa   +15 more
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Food substances alter gut resistome: Mechanisms, health impacts, and food components. [PDF]

Compr Rev Food Sci Food Saf
Abstract Antibiotics are effective in treating bacterial infections, but their widespread use has spurred antibiotic resistance, which is linked closely with human disease. While dietary components are known to influence the gut microbiome, specific effects on the gut resistome—the collection of antibiotic‐resistant genes in the gut—remain ...
Liang Z, Liang Z, Hu HW, Howell K, Fang Z, Zhang P.   +5 more
europepmc   +2 more sources

Pharmaceutical properties and toxicology ofDioclea grandiflora

Pharmaceutical Biology, 2013
Since the beginning of civilization, herbal medicines have been an important source for human beings to treat their ailments. Despite the large number of synthetic remedies available in the market, the use of plants is seen as a great challenge in the search for new substances endowed with therapeutic properties. One example is Dioclea grandiflora Mart.
Rita de Cássia da Silveira E, Sá, Reinaldo Nóbrega de, Almeida, Jnanabrata, Bhattacharyya   +2 more
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Atividade hemaglutinante em sementes de Dioclea rostrata Benth

Acta Botânica Brasílica, 1990
Sementes de Dioclea rostrata Benth. Têm uma lectina que é melhor extraída em tampão acetato de sódio a pH 4,0 e é seletivamente adsorvida em Sephadex G-50, apresentando um alto título de hemaglutinação contra eritrócitos de coelho.
T.B Grangeiro, J.T.A De Oliveira, R.A Moreira, B.S Cavada   +3 more
doaj   +1 more source

Arctigenin Inhibits Glioblastoma Proliferation through the AKT/mTOR Pathway and Induces Autophagy

BioMed Research International, Volume 2020, Issue 1, 2020., 2020
Purpose. Arctigenin (ARG) is a natural lignan compound extracted from Arctium lappa and has displayed anticancer function and therapeutic effect in a variety of cancers. Arctigenin is mainly from Arctium lappa extract. It has been shown to induce autophagy in various cancers.
Yong’an Jiang, Jiayu Liu, Wangwang Hong, Xiaowei Fei, Ru’en Liu, Stefano Curcio   +5 more
wiley   +1 more source

Preliminary investigation of Dioclea reflexa seed gum as a food and potential pharmaceutical excipient

German Journal of Pharmaceuticals and Biomaterials, 2023
The chemical quality of natural gum determines its functionality and safe use. This study was to characterize some physicochemical properties and microbial load of gum obtained from Dioclea reflexa seed (DR), which has a history of folkloric use as a ...
Chukwuemeka Mbah, Ayuba Samali, Mercy I Aboh, Josephat I Ogbonna, Philip F Builders, Anthony A Attama, Sabinus I Ofoefule   +6 more
doaj   +1 more source

Immunolocalization of the Lectins P2 and P4 from Dioclea lehmanni Seeds [PDF]

Plant and Cell Physiology, 1997
Intracellular localization of the lectins P2 and P4 from Dioclea lehmanni in developing cotyledons and in mature embryo axis were analyzed by the immunogold method. In parenchyma cells of the mature cotyledons both lectins were found in the protein bodies, whereas in immature cotyledons and in mature embryo axis these lectins were exclusively localized
L M, Melgarejo, G, Pérez
openaire   +2 more sources

The effect of Cratylia floribunda lectin on renal hemodynamics and ion transport

Brazilian Journal of Pharmaceutical Sciences, 2015
Lectins have been described as glycoproteins that reversibly and specifically bind to carbohydrates. Legume lectins isolated from the subtribe Diocleinae (Canavalia, Dioclea andCratylia) are structurally homologous with respect to their primary ...
Alexandre Havt, Ana Maria Sampaio Assreuy, Nilberto Robson Falcão do Nascimento, Manassés Claudino Fonteles, Lívia de Paula Pereira, Sandra Maria Nunes Monteiro, Paulo Sergio Ferreira Barbosa, Kyria Santiago do Nascimento, Benildo Sousa Cavada, Alice Maria Costa Martins, Helena Serra Azul Monteiro   +10 more
doaj   +1 more source

Antinociceptive and Toxicological Effects ofDioclea grandifloraSeed Pod in Mice [PDF]

Journal of Biomedicine and Biotechnology, 2010
The acute treatment of mice with an ethanolic extract from the seed pod ofDioclea grandiflora(EDgP) at doses of 75, 150 and 300 mg/kg by intraperitoneal administration produced a significant antinociceptive effect as displayed by the acetic acid-induced writhing test and the formalin test.
Sá, Rita de Cássia da Silveira e, de Oliveira, Leandra Eugênia Gomes, de Farias Nóbrega, Franklin Ferreira, Bhattacharyya, Jnanabrata, de Almeida, Reinaldo Nóbrega   +4 more
openaire   +2 more sources