Results 11 to 20 of about 16,583 (254)
Scientific Reports, 2023 Cyanophycin is a bacterial biopolymer used for storage of fixed nitrogen. It is composed of a backbone of L-aspartate residues with L-arginines attached to each of their side chains.
Itai Sharon, T. Martin Schmeing
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Crystal structure and functional characterization of an isoaspartyl dipeptidase (CpsIadA) from Colwellia psychrerythraea strain 34H. [PDF]
PLoS ONE, 2017 Isoaspartyl dipeptidase (IadA) is an enzyme that catalyzes the hydrolysis of an isoaspartyl dipeptide-like moiety, which can be inappropriately formed in proteins, between the β-carboxyl group side chain of Asp and the amino group of the following amino ...
Sun-Ha Park +6 more
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Frontiers in Microbiology, 2020 In fungi, peptidases play a crucial role in adaptability. At present, the roles of peptidases in ultraviolet (UV) and thermal tolerance are still unclear. In this study, a C69-family cysteine dipeptidase of the entomopathogenic fungus Metarhizium acridum,
Juan Li +11 more
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Pharmaceuticals, 2023 Dipeptidase 2 (DPEP2) is a dipeptidyl peptidase that plays an important role in the hydrolysis of leukotriene D4 (LTD4) to leukotriene E4 (LTE4). Previous studies have suggested that LTD4 promotes tumor progression and survival in non-small cell lung ...
Xiangqian Zhang +4 more
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Pharmaceutics, 2023 The dipeptidase angiotensin-I-converting enzyme (ACE) pre-incubation, liquid chromatography- mass spectrometry (LC-MS), and stable-isotope labeling were integrated for an efficient screening of ACE’s exogenous substrates from milk hydrolysate. Using this
Ju-Hsuan Huang +2 more
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Porto-sinusoidal vascular disorder in a pediatric patient with prolidase deficiency: A case report. [PDF]
JPGN RepAbstract Prolidase deficiency (PD) is a rare autosomal recessive disorder affecting collagen turnover, leading to diverse clinical manifestations including dermatologic lesions, hepatosplenomegaly, and vascular anomalies. Liver involvement in PD is poorly understood, with few reported cases.
Castro M +5 more
europepmc +2 more sources
Hemodynamic molecular imaging of tumor-associated enzyme activity in the living brain
eLife, 2021 Molecular imaging could have great utility for detecting, classifying, and guiding treatment of brain disorders, but existing probes offer limited capability for assessing relevant physiological parameters.
Mitul Desai +7 more
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Kidney surveillance in the spotlight: contrast-induced acute kidney injury illuminated [PDF]
, 2018 Acute kidney injury comprises a heterogeneous group of conditions characterized by a sudden decrease in renal function over hours to days. Contrast-induced acute kidney injury (CI-AKI) is caused by radiographic contrast agents used in diagnostic imaging.
Atkinson, Simon J.
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Co-Catalytic Metallopeptidases as Pharmaceutical Targets [PDF]
, 2003 Understanding the reaction mechanism of co-catalytic metallopeptidases provides a starting point for the design and synthesis of new molecules that can be screened as potential pharmaceuticals. Many of the enzymes that contain co-catalytic metallo-active
Bzymek, Krzysztof P. +2 more
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The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae [PDF]
, 2005 Background Members of the M2 family of peptidases, related to mammalian angiotensin converting enzyme (ACE), play important roles in regulating a number of physiological processes.
Burnham, S. +4 more
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