Results 21 to 30 of about 16,583 (254)

DIPEPTIDYL DIPEPTIDASE-4: VIEW OF THE CLINICAL PHARMACOLOGIST

open access: yesМедицинский совет, 2016
A deeper understanding of the pathogenesis of the 2nd type diabetes mellitus, including postprandial control of glucose homeostasis has led to new treatment strategies aimed at overcoming the dysfunction in the pancreatic islets and, in particular ...
N. B. LAZAREVA
doaj   +1 more source

Association Between Serum Carnosinase Concentration and Activity and Renal Function Impairment in a Type-2 Diabetes Cohort

open access: yesFrontiers in Pharmacology, 2022
Introduction: Genetic studies have identified associations of carnosinase 1 (CN1) polymorphisms with diabetic kidney disease (DKD). However, CN1 levels and activities have not been assessed as diagnostic or prognostic markers of DKD in cohorts of ...
Jiedong Qiu   +8 more
doaj   +1 more source

Diferenças entre os sexos na atividade da enzima conversora de angiotensina e na pressão arterial em crianças: um estudo observacional Gender differences in serum angiotensin-converting enzyme activity and blood pressure in children: an observational study

open access: yesArquivos Brasileiros de Cardiologia, 2008
FUNDAMENTO: A enzima conversora da angiotensina (ECA), principal enzima do sistema renina-angiotensina (SRA), desempenha um papel importante na regulação da pressão arterial. A atividade enzimática da ECA e sua relação com a pressão arterial (PA) durante
Patricia Landazuri   +2 more
doaj   +1 more source

Levels of angiotensin-converting enzyme 1 and 2 in serum and urine of children with Sickle Cell Disease

open access: yesBrazilian Journal of Nephrology, 2021
Introduction: Sickle cell nephropathy begins in childhood and presents early increases in glomerular filtration, which, over the long term, can lead to chronic renal failure.
Ho Chi Hsien   +5 more
doaj   +2 more sources

Interactions between the endocrine and immune systems in locusts [PDF]

open access: yes, 2003
The prophenoloxidase cascade in the haemolymph of mature adult Locusta migratoria migratorioides (R & F) is activated in response to injection of laminarin, a -1,3 glucan.
Chandrakant, S.   +3 more
core   +1 more source

Analysis of Peptides in Fermented Walnut Meal Contributing to Maintain Healthy Blood Glucose Levels and Underlying hypoglycemic Mechanism [PDF]

open access: yesShipin Kexue
This study was undertaken in order to select peptides with blood glucose regulatory activity from fermented walnut meal with fungi. Animal feeding trials were conducted for overall evaluation of the crude peptide extract, which was subsequently ...
LIU Yingying, PANG Xiaoyu, GUO Congcong, TAN Jianxin, TIAN Yiling
doaj   +1 more source

Inborn errors in the metabolism of glutathione

open access: yesOrphanet Journal of Rare Diseases, 2007
Glutathione is a tripeptide composed of glutamate, cysteine and glycine. Glutathione is present in millimolar concentrations in most mammalian cells and it is involved in several fundamental biological functions, including free radical scavenging ...
Larsson Agne, Ristoff Ellinor
doaj   +1 more source

Muscle carnosine metabolism and β-alanine supplementation in relation to exercise and training [PDF]

open access: yes, 2010
Carnosine is a dipeptide with a high concentration in mammalian skeletal muscle. It is synthesized by carnosine synthase from the amino acids L-histidine and beta-alanine, of which the latter is the rate-limiting precursor, and degraded by carnosinase ...
Baguet, Audrey   +3 more
core   +2 more sources

Inhibition of Human Cathepsins B and L by Caffeic Acid and Its Derivatives

open access: yesBiomolecules, 2020
Caffeic acid (CA) and its derivatives caffeic acid phenethyl ester (CAPE) and chlorogenic acid (CGA) are phenolic compounds of plant origin with a wide range of biological activities. Here, we identify and characterize their inhibitory properties against
Liza Ulčakar, Marko Novinec
doaj   +1 more source

Contribution of exopeptidases to formation of nonprotein nitrogen during ensiling of alfalfa [PDF]

open access: yes, 2011
The experiment was conducted to investigate the exopeptidase classes in alfalfa (Medicago sativa L.) leaves, and to determine their contribution to the formation of nonprotein nitrogen (NPN) components during ensiling.
Cheng, W.   +6 more
core   +1 more source

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