Results 51 to 60 of about 16,583 (254)

Proteomic Analysis of Fresh and Liquid-Stored Boar Spermatozoa

open access: yesAnimals, 2020
In this study comparative proteomics was used to define changes in the expression of the spermatozoa proteins during liquid storage. Semen from eight boars was analyzed on the day of collection and after liquid preservation at 15−17 °C for ...
Blanka Premrov Bajuk   +6 more
doaj   +1 more source

Effects of varicocele and microsurgical varicocelectomy on the metabolites in semen

open access: yesScientific Reports, 2022
The influence of varicocele and microsurgical varicocelectomy on semen quality remains unclear. Few studies have investigated the relationship between semen metabolism and the abnormalities in reproductive function caused by varicocele, however, there is
Xinzong Zhang   +13 more
doaj   +1 more source

Plasma extracellular vesicles from APOE3 Christchurch carriers display a protective phenotype in early stages of autosomal dominant Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION The PSEN1E280A mutation causes autosomal dominant Alzheimer's disease (ADAD) with predictable onset, enabling presymptomatic studies. Extracellular vesicles (EVs) are emerging biomarkers of cognitive decline, but their role in early ADAD is unclear.
Lina Pineda‐Lopez   +14 more
wiley   +1 more source

The ester hydrolytic and synthetic activities of X-prolyl dipeptidyl peptidase from Streptococcus thermophilus : a thesis presented in partial fulfillment of the requirements for the degree of Master of Science in Biochemistry at Massey University, New Zealand [PDF]

open access: yes, 2003
X-prolyl dipeptidyl peptidase (EC 3.4.14.11), or PepX, is a dipeptidase found in most dairy lactic acid bacteria that hydrolyses N-terminal dipeptides from larger peptides where proline is the residue penultimate to the scissile bond.
Bennett, Matthew David
core  

Angiotensin-I-Converting Enzyme and its Relatives [PDF]

open access: yes, 2011
Angiotensin-I-converting enzyme (ACE) is a monomeric, membrane-bound, zinc- and chloridedependent peptidyl dipeptidase that catalyzes the conversion of the decapeptide angiotensin I to the octapeptide angiotensin II, by removing a carboxy-terminal ...
Riordan, James Francis
core   +1 more source

Identification and Characterization of Three Novel Biomarkers for Mixed/Cholestatic Drug‐Induced Liver Injury

open access: yesHepatology Research, Volume 56, Issue 1, Page 111-124, January 2026.
Three metabolites, pyroglutamylglycine (pyroGluGly), phenylalanine (Phe), and phenylalanyltryptophan (PheTrp), were identified as candidate DILI biomarkers. The serum concentrations of pyroGluGly, Phe, and PheTrp demonstrated a high differentiating ability in patients with mixed and cholestatic DILI compared with those in patients who recovered from ...
Kosuke Saito   +22 more
wiley   +1 more source

Expanding the Immunologic and Neuronal Landscape of IgE‐Mediated Anaphylaxis

open access: yesImmunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Anaphylaxis is a life‐threatening immunoglobulin E (IgE)‐mediated type I hypersensitivity reaction with rising prevalence and burden. It involves mast cell degranulation upon cross‐linking of antigen on mast cell‐bound IgE. Mechanisms of IgE‐mediated anaphylaxis remain incompletely understood, particularly the induction of systemic symptoms ...
Ruchi Biswas   +2 more
wiley   +1 more source

Spectrum of effects of dipeptidyl peptidase-4 inhibitors: within and beyond glycemic control (part 2)

open access: yesСахарный диабет
To mark the 20th anniversary of clinical use of dipeptidase-4 inhibitors (DPP-4i), the understanding of the spectrum of effects (metabolic, clinical, biological) beyond the initially defined glycemic control is expanded, and the possibilities and ...
L. A. Ruyatkina, D. S. Ruyatkin
doaj   +1 more source

Aristolochic acid induces chronic kidney disease in ace knockout mice

open access: yesInternational Journal of Preventive Medicine, 2021
Background: Aristolochic acid I (AAI) is an extract from Chinese herbs that causes progressive interstitial nephritis. The aim of this research is to know whether chymases play the crucial role in AAI-induced nephropathy.
Jia-Ping Wu
doaj   +1 more source

Early Nutritional Programing: Unlocking the Potential of Fish for Sustainable Aquaculture

open access: yesAquaculture Nutrition, Volume 2026, Issue 1, 2026.
Nutritional programing, which explores the link between early nutritional conditions and their long‐term effects on animals, is a developing field within fish biology. Suboptimal nutritional status during early life is strongly associated with a higher risk of metabolic consequences later in life, including permanent growth retardation, impaired neural
Shivendra Kumar   +5 more
wiley   +1 more source

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