Results 31 to 40 of about 1,322 (179)
This study presents the first spatially resolved proteomic map of diabetic vasculopathy, identifying distinct molecular signatures in aortic regions. The glucocorticoid receptor/dipeptidase 1 (GR/DPEP1) axis was identified as a novel driver of diabetic vascular inflammation and dysfunction.
Chak Kwong Cheng +9 more
wiley +1 more source
Role of Cysteinyl Leukotrienes in Food Allergy and Anaphylaxis: A Potential Therapeutic Target
Allergy, EarlyView.
A. Weingaertner, T. Eiwegger
wiley +1 more source
Biochemical and x-ray crystallographic studies on dipeptidases PeptidaseV and Isoaspartyl Dipeptidase [PDF]
Zur Zeit sind drei humane Vertreter der Kollagenasen besonders gut untersucht, nämlich Kollagenase-1, -2 und -3, die alle in der Lage sind, fibrilläres Kollagen (Kollagen I - III) abzubauen, obgleich mit unterschiedlicher Effizienz.
Jozic, Daniela
core
This randomized, double‐blind, placebo‐controlled trial demonstrated that probiotic supplementation in individuals with non‐celiac gluten/wheat sensitivity improved tolerance to gluten reintroduction in nearly half of participants. The effect was associated with beneficial shifts in gut microbiome composition and function, including enhanced microbial ...
Ilario Ferrocino +14 more
wiley +1 more source
Gluten proteins typically have a large proline content in their amino acid sequences which yields high resistivity to hydrolysis from regular digestive enzymes within humans. As a result, Celiac disease exists in genetically predisposed individuals as a
Lee, Brian
core
ABSTRACT Malaria, a febrile disease caused by the Plasmodium parasites and transmitted by mosquitoes, is a leading cause of mortality in children under 5 in endemic countries. The widespread deployment of insecticide‐treated bed nets (ITNs) has significantly reduced malaria transmission, but rising levels of insecticide resistance threaten to halt the ...
Harun N. Njoroge +21 more
wiley +1 more source
Prolyl-rich peptides derived from hydrolysates of bovine caseins have been previously shown to inhibit angiotensin converting enzyme (ACE) activity, suggesting that they may also be able to inhibit the enzymatic activities of prolyl-specific peptidases ...
Robert, M.C. +5 more
core +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Prolyl-rich peptides derived from hydrolysates of bovine caseins have been previously shown to inhibit angiotensin converting enzyme (ACE) activity, suggesting that they may also be able to inhibit the enzymatic activities of prolyl-specific peptidases ...
Marcel A. Juillerat (2238703) +2 more
core +1 more source
SummaryHemoglobin digestion is an essential process for blood-feeding parasites. Using chemical tools, we deconvoluted the intracellular hemoglobinolytic cascade in the tick Ixodes ricinus, a vector of Lyme disease and tick-borne encephalitis.
Nussbaumerová, Martina +10 more
core +1 more source

