Results 41 to 50 of about 59,947 (268)

Surface nucleated growth of dipeptide fibres [PDF]

, 2013
We report the surface nucleated growth of self-assembled dipeptide films. The seeding-layer was a thin dipeptide film with a globular structure. Placing the seeding-layer in contact with dipeptide led to growth of fibres overnight.
Adams, Dave J., McDonald, Shane F., Cameron, Petra J., Chen, Lin, Johnson, Eleanor K., Kubiak, Peter S.   +5 more
core   +2 more sources

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Chirality Induction in Bioorganometallic Conjugates

Inorganics, 2018
Considerable attention has been given to the research field of bioorganometallic chemistry, which is a hybrid chemistry field between biology and organometallic chemistry.
Toshiyuki Moriuchi, Satoshi D. Ohmura, Takayo Moriuchi-Kawakami   +2 more
doaj   +1 more source

New Copper(II)-L-Dipeptide-Bathophenanthroline Complexes as Potential Anticancer Agents—Synthesis, Characterization and Cytotoxicity Studies—And Comparative DNA-Binding Study of Related Phen Complexes

Molecules, 2023
Searching for new copper compounds which may be useful as antitumor drugs, a series of new [Cu(L-dipeptide)(batho)] (batho:4,7-diphenyl-1,10-phenanthroline, L-dipeptide: Gly-Val, Gly-Phe, Ala-Gly, Ala-Ala, Ala-Phe, Phe-Ala, Phe-Val and Phe-Phe) complexes
Carlos Y. Fernández, Natalia Alvarez, Analu Rocha, Javier Ellena, Antonio J. Costa-Filho, Alzir A. Batista, Gianella Facchin   +6 more
doaj   +1 more source

Beyond Primary Nucleation: Molecular Basis of Peptide Crystal Secondary Nucleation at Soft Interface

Advanced Functional Materials, EarlyView.
High spatiotemporal‐resolution atomic force microscopy directly resolved peptide secondary nucleation (SN) and growth characteristics and mechanisms on HOPG. The landscape of peptide nucleation sites, growth dynamics, molecular‐scale structures, phase transitions, and cross‐seeding processes were realized.
Linhao Sun, Abilesh Kumar, Ayhan Yurtsever   +2 more
wiley   +1 more source

On the Mechanical Properties of N-Functionalised Dipeptide Gels

Molecules, 2019
The properties of a hydrogel are controlled by the underlying network that immobilizes the solvent. For gels formed by the self-assembly of a small molecule, it is common to show the primary fibres that entangle to form the network by microscopy, but it ...
Ana M. Fuentes-Caparrós, Kate McAulay, Sarah E. Rogers, Robert M. Dalgliesh, Dave J. Adams   +4 more
doaj   +1 more source

Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

Advanced Science, EarlyView.
This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li, Kuanhui Gao, Mengjie Wang, Songlin Liang, Dandan Li, Guoqing Tan, Haipeng Xue, Yujie Liu, Peng Zhang, Zhanwang Xu, Wenxiang Cheng, Yongjun Wang, Nianhu Li   +12 more
wiley   +1 more source

Dipeptide-Derived Alkynes as Potent and Selective Irreversible Inhibitors of Cysteine Cathepsins

The potential of designing irreversible alkyne-based inhibitors of cysteine cathepsins by isoelectronic replacement in reversibly acting potent peptide nitriles was explored.
Christian Trapp (10999131), Reik Löser (2309806), Maryann Morales (8648817), Jens Pietzsch (1562308), Martin Köckerling (1589749), Gloria Ruiz-Gómez (2245177), Robert Wodtke (2635681), Lydia Behring (14716359), Klaus Kopka (430828), M. Teresa Pisabarro (166474)   +9 more
core   +2 more sources

Phylogenetic relationships between (A) dipeptide transporter permeases and (B) dipeptide substrate-binding proteins.

, 2014
Phylogenetic relationships between (A) dipeptide transporter permeases and (B) dipeptide substrate-binding proteins.
Thilo Köhler (249215), Daniel Pletzer (648371), Michael Mourez (246675), Helge Weingart (648374), Malcolm G. P. Page (648373), Corinne Lafon (648372), Yvonne Braun (332810)   +6 more
core   +1 more source

β‐Aminosäuren, VIII. Mitteil.: β‐Aminosäure‐Dipeptide

, 1956
Es wird die Synthese der beiden gemischten Dipeptide mit den Komponenten DL‐α‐Alanin und β‐Alanin beschrieben sowie 6 weiterer Dipeptide, welche aus je 2 β‐Aminosäuren zusammengesetzt ...
Birkofer, L., Hartwig, I.
core   +1 more source