Results 201 to 210 of about 65,496 (283)

Computational Analysis of Balanites aegyptiaca Phytochemicals as Inhibitors of Human Pancreatic α‐Amylase

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT Balanites aegyptiaca (BA) is a plant of paramount potential for the management of diabetes mellitus. The study investigates in silico studies of natural library compounds including that from BA with the assistance of network pharmacology. Balanitesin (compound 1) exhibited the highest docking score and binding free energy (∆G) values of −14 ...
Surendra Kumar Gautam, Rakesh Kumar Paul, Smita Jain, Iqrar Ahmad, Ammar A. Razzak Mahmood, Harun Patel, Penke Vijaya Babu, Muhammad Wahajuddin, Kaisar Raza   +8 more
wiley   +1 more source

Cardiovascular Events and Heart Failure in Patients With Type 2 Diabetes Treated With Dipeptidyl Peptidase-4 Inhibitors: A Meta-Analysis. [PDF]

Curr Ther Res Clin Exp
Tuersun A, Cui S, Han L, Aikebaier A, Shi Y, Cheng G, Cheng L, Ma G.   +7 more
europepmc   +1 more source

Vildagliptin and Omarigliptin Differentially Bind to DPP‐4 Homodimers and Modulate Osteoclast‐Mediated Bone Resorption

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
Vildagliptin and omarigliptin, dipeptidyl peptidase‐4 (DPP‐4) inhibitors, have differential effects on bone cells. Although vildagliptin improved the bone microstructure of high‐fat diet‐fed rats, it was unable to downregulate osteoclastogenesis or the expression of key osteoclast transcripts.
Ratchaneevan Aeimlapa, Jiraporn Panmanee, Jarinthorn Teerapornpuntakit, Kannikar Wongdee, Jirawan Thongbunchoo, Nattapon Panupinthu, Saovaros Svasti, Nattayaporn Apaijai, Piangkwan Sa‐nguanmoo, Siriporn Chattipakorn, Nipon Chattipakorn, Narattaphol Charoenphandhu   +11 more
wiley   +1 more source

Sodium-glucose cotransporter-2 inhibitors and dipeptidyl peptidase-4 inhibitors on diabetic macular edema and the need for intravitreal injection. [PDF]

Int J Ophthalmol
Chung YR, Kim C, Lee E, Lee K.
europepmc   +1 more source

Dipeptidyl peptidase‐4 inhibitor approaches

Journal of Diabetes, 2016
openaire   +1 more source

Diabetic Neuropathy Is Associated With Lower Bone Mineral Density and Higher Fall Risk in Young Elderly Adults With Type 2 Diabetes

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 2, February 2026.
ABSTRACT Background and Aim Diabetic neuropathy (DN) is a recognised risk factor for fragility fractures. However, the mechanisms linking DN, bone health, and falling risk remain unclear. We aimed to assess bone health and risk of falls, with their contributing factors, in young elderly patients with type 2 diabetes (T2D) and mild‐to‐moderate DN ...
Luca D'Onofrio, Rocco Amendolara, Antonio Siena, Alessandro Latino, Renata Risi, Angela Balena, Simona Zampetti, Davide Masi, Marianna Alfonsi, Barbara La Scaleia, Mikiko Watanabe, Myrka Zago, Francesco Lacquaniti, Ernesto Maddaloni, Raffaella Buzzetti   +14 more
wiley   +1 more source

Unique Role of Proximal Tubule Dipeptidyl Peptidase 4 on Blood Pressure, Renal Sodium Handling, and Na⁺/H⁺ Exchanger Isoform 3 Phosphorylation. [PDF]

Acta Physiol (Oxf)
Martins FL, Ribeiro-Silva JC, de Jesus EF, Nistala R, Girardi ACC.   +4 more
europepmc   +1 more source

Wild Prunus cerasifera Ehrh. Polyphenols Alleviate Hyperglycemia in Type 2 Diabetes Mellitus Mice via Modulating Gut Microbiota‐SCFAs‐PI3K/Akt/TBC1D4 Pathway

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
WPPE treatment significantly alleviated type 2 diabetes by improving SCFAs and gut microbiota composition and promoted glycogen synthesis by regulating the PI3K/AKT/TBC1D4 pathway. WPPE also improved liver function and reduced oxidative stress and inflammation. ABSTRACT Our previous work demonstrated that wild Prunus cerasifera Ehrh.
Xinpeng Cheng, Xing Xie, Shibo Luo, Quanyuan Xie, Haiyan Xiang, Chunyan Peng, Qiao Ding, Hongbing Fan, Wei Liu, Lu Zhang   +9 more
wiley   +1 more source

Cardiovascular Events in Individuals Treated With Sulfonylureas or Dipeptidyl Peptidase 4 Inhibitors.

JAMA Netw Open
Turchin A, Petito LC, Hegermiller E, Carnahan R, DeVries A, Goel S, Lansang MC, McDonnell ME, Nair V, Priest E, Willey VJ, Kaul AF, Hernán MA.   +12 more
europepmc   +1 more source

Dipeptidyl peptidase-4 (DPP-4; CD26) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source