Results 11 to 20 of about 115,987 (377)
Nature Communications, 2021 Mechanisms triggering hypertrophic scar formation remain poorly understood. Here the authors perform scRNA-seq on mature human hypertrophic scars and developing scars in mice to identify the serine proteases dipeptidyl-peptidase 4 and urokinase as key ...
Vera Vorstandlechner +12 more
doaj +2 more sources
Neural Regeneration Research, 2019 Repositioning of dipeptidyl peptidase-4 inhibitors and glucagon like peptide-1 receptor agonists is a breakthrough in the field of neural regeneration research increasing glucagon like peptide-1 bioavailability, hence its neuroprotective activities.
Shaker A Mousa, Bassam M Ayoub
doaj +2 more sources
The emerging role of dipeptidyl peptidase 3 in pathophysiology [PDF]
The FEBS Journal, 2022 Dipeptidyl peptidase 3 (DPP3), a zinc‐dependent aminopeptidase, is a highly conserved enzyme among higher animals. The enzyme cleaves dipeptides from the N‐terminus of tetra‐ to decapeptides, thereby taking part in activation as well as degradation of ...
Grazia Malovan +6 more
openalex +2 more sources
Dipeptidyl Peptidase-4 Inhibitor-Associated Bullous Pemphigoid
Frontiers in Immunology, 2019 Bullous pemphigoid (BP) is an organ-specific autoantibody-mediated blistering skin disease that mainly affects the elderly. Typical clinical features include the widespread blisters, often preceded by and/or associated with itchy urticarial or eczema ...
Kaisa Tasanen +2 more
doaj +3 more sources
JAMA Network Open, 2022 This cohort study assesses whether treatment with glucagon-like peptide-1 (GLP-1) receptor agonists is associated with better outcomes than treatment with dipeptidyl peptidase-4 (DPP-4) inhibitors among patients with type 2 diabetes and advanced-stage ...
Jia-Jin Chen +12 more
semanticscholar +1 more source
Emerging Role of Dipeptidyl Peptidase-4 in Autoimmune Disease
Frontiers in Immunology, 2022 Dipeptidyl-peptidase IV (DPP4), originally identified as an aminopeptidase in 1960s, is an ubiquitously expressed protease presented as either a membrane-bound or soluble form.
Jie Huang +7 more
semanticscholar +1 more source
Dipeptidyl Peptidase 4 (DPP4) as A Novel Adipokine: Role in Metabolism and Fat Homeostasis
Biomedicines, 2022 Dipeptidyl peptidase 4 (DPP4) is a molecule implicated in the regulation of metabolic homeostasis and inflammatory processes, and it exerts its main action through its enzymatic activity.
I. Barchetta +3 more
semanticscholar +1 more source
Role of Dipeptidyl Peptidase 4 Inhibitors in Antidiabetic Treatment
Molecules, 2022 In recent years, important changes have occurred in the field of diabetes treatment. The focus of the treatment of diabetic patients has shifted from the control of blood glucose itself to the overall management of risk factors, while adjusting blood ...
Rui-li Yin +4 more
semanticscholar +1 more source
British medical journal, 2022 Objective To examine the association between dipeptidyl peptidase-4 inhibitors and gallbladder or biliary diseases. Design Systematic review and pairwise and network meta-analysis.
Liyun He +8 more
semanticscholar +1 more source
Beneficial effects of dipeptidyl peptidase-4 inhibitors in diabetic Parkinson's disease.
Brain : a journal of neurology, 2021 Dipeptidyl peptidase 4 (DPP4) inhibitors are widely used hypoglycaemic agents and improve glucose metabolism by enhancing the bioavailability of active glucagon-like peptide-1.
Seong Ho Jeong +8 more
semanticscholar +1 more source