Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa +9 more
wiley +1 more source
Homoterpene Biosynthesis in Fungi. [PDF]
Zhou L +5 more
europepmc +1 more source
Inflammatory niches as spatial drivers of disease mechanisms and targets for personalized treatment
This study provides a comprehensive review of how spatial transcriptomics reveals disease‐specific inflammatory niches across multiple skin disorders, highlighting key immune–stromal, neuro–immune and metabolic interactions that were previously unappreciated in non‐spatial analyses. Abstract Disease states are increasingly recognized as being shaped by
Rundong Jiang +3 more
wiley +1 more source
Efficacy and safety of emulsified microsomal ferric pyrophosphate vs. Ferrous Ascorbate in pregnancy with iron-deficiency anemia- a randomized, comparative study. [PDF]
Patki A +5 more
europepmc +1 more source
Heterogeneity of iridoid biosynthesis in catmints: Molecular background in a phylogenetic context
Evolutionary gains and losses of key biosynthetic genes likely resulting from multiple independent evolutionary events explain why certain Nepeta (catnip) species produce both the active, cat‐attracting nepetalactones and sugar‐bound iridoids, while others make only the sugar‐bound forms, and some have lost iridoid production entirely.
Tijana Banjanac +15 more
wiley +1 more source
Enhancing the Nucleoside Analog Response with Translational Therapeutic Approaches to Overcome Resistance. [PDF]
Thibodeau J +9 more
europepmc +1 more source
Engineering the bacterial nutrition strategy to control plant diseases
This commentary on Wang et al. (2025) and Phan et al. (2025) highlights previously undiscovered Xanthomonas pathways for nutrition acquisition, explains how Xanthomonas bacteria hijack host molecular machinery through their effector proteins, and discusses how these studies can be used to develop new disease resistance mechanisms.
Muhammad Arslan Mahmood +2 more
wiley +1 more source
Structure-function insights into the dual role of African swine fever virus pB318L: A typical geranylgeranyl-diphosphate synthase and a nuclear import protein. [PDF]
Zhao HF +9 more
europepmc +1 more source
Summary In plants, hypoxia sensing is controlled by the stabilization of group VII ethylene response factors (ERF‐VIIs), which are post‐translationally activated by the mitogen‐activated protein kinases (MAPKs) MPK3 and MPK6. However, how plants fine‐tune the MPK3/MPK6‐mediated phosphorylation of ERF‐VIIs to maintain cellular homeostasis remains ...
De‐Mian Zhou +9 more
wiley +1 more source

