Toxin-Based Vaccines (Diphtheria, Tetanus, Pertussis)
1999Corynebacterium diphtheriae, Clostridium tetani, and Bordetella pertussis produce potent toxins that are entirely or in part responsible for the severe diseases caused by these micro-organisms. The clinical manifestations of diphtheria and tetanus can be thoroughly reproduced by the systemic administration of the toxins.
R. Rappuoli, M. Pizza
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Diphtheria-tetanus-pertussis vaccine mortality
Ugeskrift for LægerAlthough the diphtheria-tetanus-pertussis (DTP) vaccine is lifesaving through decades, it has been voiced that the vaccine is associated with 50% increase in mortality, an alleged negative non-specific vaccine effect prone to girls. Post hoc analyses of historical observational data supporting the hypothesis of the DTP vaccine having detrimental ...
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The value of booster vaccinations against diphtheria, tetanus, pertussis and poliomyelitis
Journal of preventive medicine and hygiene, 2008No ...
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A laboratory study of the toxicity of some diphtheria-tetanus-pertussis vaccines
Journal of Biological Standardization, 1981A battery of 14 laboratory tests has been used to examine the toxicities and pharmacological properties of some British and North-American diphtheria-tetanus-pertussis (DTP) vaccines. In most of the tests the activities of the vaccines were found to extend over an appreciable range but to be inconsistent in that, in the case of each vaccine, high ...
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Characterization of the febrile response to diphtheria‐tetanus‐pertussis vaccination
International Journal of Risk & Safety in Medicine, 2000To evaluate the incidence and course of fever following DTP vaccination we prospectively studied 430 healthy infants who received the four doses of vaccine at ages 2, 4, 6 and 12 months. Each infant was followed one week before and three days after immunization.
Lutfi Jaber, Shai Ashkenazi
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Local massage after vaccination enhances the immunogenicity of diphtheria-tetanus-pertussis vaccine
The Pediatric Infectious Disease Journal, 1995The effect of local massage on adverse reactions and immunogenicity of diphtheria-tetanus-pertussis vaccine was investigated. After diphtheria-tetanus-pertussis vaccination 327 infants were either massaged or not, and adverse reactions were evaluated. Local pain and fever were more frequent in the massage group.
C Y, Hsu +5 more
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The WHO Review of the Possible Nonspecific Effects of Diphtheria-Tetanus-Pertussis Vaccine
Pediatric Infectious Disease Journal, 2016World Health Organization recently reviewed the possible nonspecific effects of diphtheria-tetanus-pertussis (DTP) vaccine. The results were considered inconsistent though most studies suggested deleterious effects. We examined whether inconsistencies in results reflected differences in effect of DTP or differences in the methodology used in different ...
Peter Aaby +2 more
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Serum antibodies to diphtheria-tetanus-pertussis vaccine components in Argentine children
Infection, 1997The Argentine vaccination schedule against diphtheria, tetanus and pertussis (DTP) recommends three doses of DTP vaccine at 2, 4 and 6 months of age, two boosters at 18 months and 6 years, a booster dose of tetanus vaccine every 10 years and two doses during pregnancy. To evaluate the effect of this schedule, antibodies against pertussis toxin (PT) and
M, Pasetti +3 more
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[Tetravalent diphtheria, tetanus, pertussis and inactivated poliomyelitis vaccine].
Archives francaises de pediatrie, 1990Two hundred forty-nine infants were immunized after being randomly allocated to the classical Tetracoq vaccine or to inactivated poliomyelitis vaccines prepared on monkey kidney cells or on Vero-type continuous cell lines either mixed with DPT or placed in a 2-compartment syringe separating (by-pass) the polio vaccine from the DPT.
C, Fillastre, P, Brégère, N, Guérin
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Erratum. Editorial: Diphtheria-tetanus-pertussis vaccine mortality
Ugeskrift for LægerReferences to personal communication in the originally published article has been deleted, as permission was not available. This does not result in changes to the rest of the article text. Ugeskrift for Læger apologizes for the error. The original version of the article has been updated.
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