Results 1 to 10 of about 64,484 (166)

Prevalence and characterization of pertactin deficient Bordetella pertussis strains in Brazil, a whole-cell vaccine country

open access: yesVaccine: X, 2021
Many countries have reported antigenic divergence among circulating Bordetella pertussis strains, mainly in those countries which introduced the acellular pertussis (aP) vaccine. This phenomenon can be seen, for example, with the recent rise of pertactin
Daniela Leite   +9 more
doaj   +1 more source

Hospital-based prospective study of pertussis in infants and close contacts in Tehran, Iran

open access: yesBMC Infectious Diseases, 2021
Background Pertussis remain a global health concern, especially in infants too young to initiate their vaccination. Effective vaccination and high coverage limit the circulation of the pathogen, yet duration of protection is limited and boosters are ...
Gaelle Noel   +15 more
doaj   +1 more source

The Impact of Early Postpartum Maternal Pertussis Vaccination on the Protection of Infants: A Randomized Clinical Trial [PDF]

open access: yesIranian Journal of Immunology, 2019
Background: Despite primary vaccination, infants under six months run a risk of infection with pertussis. Objective: To determine the impact of early postpartum maternal pertussis vaccination on protecting infants from the disease.
Ayse Kilic   +10 more
doaj   +1 more source

The Fim and FhaB adhesins play a crucial role in nasal cavity infection and Bordetella pertussis transmission in a novel mouse catarrhal infection model.

open access: yesPLoS Pathogens, 2022
Pulmonary infections caused by Bordetella pertussis used to be the prime cause of infant mortality in the pre-vaccine era and mouse models of pertussis pneumonia served in characterization of B. pertussis virulence mechanisms.
Jana Holubova   +5 more
doaj   +1 more source

A novel vaccine formulation candidate based on lipooligosaccharides and pertussis toxin against Bordetella pertussis

open access: yesFrontiers in Immunology, 2023
Pertussis is a severe human respiratory tract infectious disease caused by Bordetella pertussis that primarily affects infants and young children.
Jingjing Gao   +6 more
doaj   +1 more source

Association of Vitamin D Receptor Polymorphism with Susceptibility to Symptomatic Pertussis. [PDF]

open access: yesPLoS ONE, 2016
Pertussis, caused by infection with the gram negative B. pertussis bacterium, is a serious respiratory illness that can last for months. While B.
Wanda G H Han   +6 more
doaj   +1 more source

Pathogen analysis of pertussis-like syndrome in children

open access: yesBMC Infectious Diseases, 2020
Background The aim of the study was to identify the pathogens, in addition to bordetella pertussis (B. pertussis), which cause pertussis-like syndrome in children and to compare clinical presentation between those with B.
Wenjing Gu   +10 more
doaj   +1 more source

Burden of Pertussis in Adults Aged 50 Years and Older: A Retrospective Database Study in England

open access: yesInfectious Diseases and Therapy, 2023
Introduction Pertussis, a highly infectious respiratory disease caused by Bordetella pertussis, affects people of all ages. Older adults are particularly susceptible to its severe outcomes and complications.
Lauriane Harrington   +11 more
doaj   +1 more source

Risk factors for pertussis among children hospitalized for pertussis during 2016–2017, in Guizhou Province of China: a case-control study

open access: yesGlobal Health Journal, 2021
Aim: Pertussis is a respiratory tract infection, the vaccine for which was introduced in the Expanded Programme on Immunization (EPI) in Guizhou Province of China (hereafter referred as Guizhou) in the 1980s.
Feng Jiang   +3 more
doaj   +1 more source

Genomic epidemiology of Iranian Bordetella pertussis: 50 years after the implementation of whole cell vaccine

open access: yesEmerging Microbes and Infections, 2019
Pertussis caused by Bordetella pertussis, remains a public health problem worldwide, despite high vaccine coverage in infants and children in many countries. Iran has been using whole cell vaccine for the last 50 years with more than 95% vaccination rate
Azadeh Safarchi   +8 more
doaj   +1 more source

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