Results 21 to 30 of about 3,335 (157)

Incidence and Healthcare Burden of Pertussis among Older Adults with and without Pre-Existing Chronic Obstructive Pulmonary Disease or Asthma in South Korea

COPD, 2023
A retrospective cohort study was conducted to examine trends in the incidence and burden of pertussis among adults ≥50 years in South Korea, with/without pre-existing chronic obstructive pulmonary disease (COPD) or asthma. The nationwide Health Insurance
Jing Chen, Ju-Young Shin, Hyungwoo Kim, Ju Hwan Kim, Ahhyung Choi, Hee Jin Cheong, Yeon-Mok Oh, Adrienne Guignard, Sumitra Shantakumar   +8 more
doaj   +1 more source

The resurgence of pertussis [PDF]

Canadian Medical Association Journal, 2015
Pertussis (whooping cough) is caused by the bacterium Bordetella pertussis . In children, pertussis classically presents with paroxysms of coughing followed by a post-tussive inspiratory whooping sound.[1][1] In older individuals, its sole manifestation may be protracted cough; therefore ...
J Brad, Wiggers, Jerome A, Leis, Wayne L, Gold   +2 more
openaire   +2 more sources

Seroprevalence of IgA and IgM antibodies to Bordetella pertussis in healthy Japanese donors: Assessment for the serological diagnosis of pertussis.

PLoS ONE, 2019
Pertussis is a human respiratory infection caused by the gram-negative bacterium, Bordetella pertussis. To evaluate the pertussis burden and vaccine efficacy, diagnosis and epidemiological surveillance should be based on accurate and valid diagnostic ...
Rei Fumimoto, Nao Otsuka, Hajime Kamiya, Tomimasa Sunagawa, Keiko Tanaka-Taya, Kazunari Kamachi, Keigo Shibayama   +6 more
doaj   +1 more source

Fluorescent cAMP Analogs: Enzymatic Synthesis, Unexpected Photophysical Behavior and Protein Kinase A Recognition

Angewandte Chemie, EarlyView.
Cyclic adenosine monophosphate (cAMP) is a key cellular second messenger. Adenylyl cyclase converts emissive isomorphic nucleoside triphosphates into fluorescent cAMPs. cthAMP displays unusually high brightness compared to thATP, its precursor, enabling real‐time monitoring of enzymatic reactions.
Deyuan Cong, Victor Dubois, Jamie Y. Lam, Yitzhak Tor   +3 more
wiley   +2 more sources

Loss of multi-epitope specificity in memory CD4(+) T cell responses to B. pertussis with age. [PDF]

PLoS ONE, 2013
Pertussis is still occurring in highly vaccinated populations, affecting individuals of all ages. Long-lived Th1 CD4(+) T cells are essential for protective immunity against pertussis.
Wanda G H Han, Inonge van Twillert, Martien C M Poelen, Kina Helm, Jan van de Kassteele, Theo J M Verheij, Florens G A Versteegh, Claire J P Boog, Cécile A C M van Els   +8 more
doaj   +1 more source

Reduced IgG titers against pertussis in rheumatoid arthritis: Evidence for a citrulline-biased immune response and medication effects.

PLoS ONE, 2019
BackgroundThe antibody response to pertussis vaccination in rheumatoid arthritis is unknown, a concerning omission given the relatively low efficacy of the pertussis vaccine, a rise in pertussis infections, and a general increased susceptibility to ...
Caitlyn L Holmes, Chloe G Peyton, Amy M Bier, Tobias Z Donlon, Fauzia Osman, Christie M Bartels, Miriam A Shelef   +6 more
doaj   +1 more source

A retrospective study of acute pertussis in Hasan Sadikin Hospital–Indonesia

Journal of Acute Disease, 2015
Objective: To describe the representation of pertussis diagnosis in children. Methods: A retrospective observational study was performed on pediatric pertussis and pertussis-like syndrome registry for children
Heda Melinda Nataprawira, Evelyn Phangkawira   +1 more
doaj   +1 more source

The evolution of pertactin expression in Belgian circulating B. pertussis strains, pre- and post-COVID-19

Microbiology Spectrum
Prior to the COVID-19 pandemic, Bordetella pertussis strains not producing pertactin were globally increasing, especially in countries using the acellular pertussis vaccine. Subsequently, during the pandemic, global pertussis incidence dropped to extreme
Helena Martini, Oriane Soetens, Vili Niinikoski, Alex-Mikael Barkoff, Qiushui He, Denis Piérard, Eveline Van Honacker   +6 more
doaj   +1 more source

Bordetella pertussis Strains with Increased Toxin Production Associated with Pertussis Resurgence

Emerging Infectious Diseases, 2009
Before childhood vaccination was introduced in the 1940s, pertussis was a major cause of infant death worldwide. Widespread vaccination of children succeeded in reducing illness and death.
Frits R. Mooi, Inge H.M. van Loo, Marjolein van Gent, Qiushui He, Marieke J. Bart, Kees J. Heuvelman, Sabine C. de Greeff, Dimitri Diavatopoulos, Peter Teunis, Nico Nagelkerke, Jussi Mertsola   +10 more
doaj   +1 more source

Infant rhesus macaques as a non-human primate model of Bordetella pertussis infection

BMC Infectious Diseases, 2021
Background The prevalent resurgence of pertussis has recently become a critical public health problem worldwide. To understand pertussis pathogenesis and the host response to both the pathogen and vaccines, a suitable pertussis animal model, particularly
Wenwen Jiang, Chen Wei, Dachao Mou, Weilun Zuo, Jiangli Liang, Xiao Ma, Lichan Wang, Na Gao, Qin Gu, Peng Luo, Yan Ma, Jingyan Li, Shuyuan Liu, Li Shi, Mingbo Sun   +14 more
doaj   +1 more source