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Pertussis is a human respiratory infection caused by the gram-negative bacterium, Bordetella pertussis. To evaluate the pertussis burden and vaccine efficacy, diagnosis and epidemiological surveillance should be based on accurate and valid diagnostic ...
Rei Fumimoto +6 more
doaj +1 more source
Loss of multi-epitope specificity in memory CD4(+) T cell responses to B. pertussis with age. [PDF]
Pertussis is still occurring in highly vaccinated populations, affecting individuals of all ages. Long-lived Th1 CD4(+) T cells are essential for protective immunity against pertussis.
Wanda G H Han +8 more
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A retrospective study of acute pertussis in Hasan Sadikin Hospital–Indonesia
Objective: To describe the representation of pertussis diagnosis in children. Methods: A retrospective observational study was performed on pediatric pertussis and pertussis-like syndrome registry for children
Heda Melinda Nataprawira +1 more
doaj +1 more source
BackgroundThe antibody response to pertussis vaccination in rheumatoid arthritis is unknown, a concerning omission given the relatively low efficacy of the pertussis vaccine, a rise in pertussis infections, and a general increased susceptibility to ...
Caitlyn L Holmes +6 more
doaj +1 more source
Since 1997, an unexpected 2-5-fold increase in the incidence of pertussis has been reported in Poland in comparison with the previous 10 years, although the introduction of the diphtheria-tetanus-pertussis (DTP) vaccination in 1960 reduced the incidence of pertussis approximately 100-fold in the 1980s.
Anna, Gzyl +4 more
openaire +2 more sources
Prior to the COVID-19 pandemic, Bordetella pertussis strains not producing pertactin were globally increasing, especially in countries using the acellular pertussis vaccine. Subsequently, during the pandemic, global pertussis incidence dropped to extreme
Helena Martini +6 more
doaj +1 more source
Bordetella pertussis Strains with Increased Toxin Production Associated with Pertussis Resurgence
Before childhood vaccination was introduced in the 1940s, pertussis was a major cause of infant death worldwide. Widespread vaccination of children succeeded in reducing illness and death.
Frits R. Mooi +10 more
doaj +1 more source
Infant rhesus macaques as a non-human primate model of Bordetella pertussis infection
Background The prevalent resurgence of pertussis has recently become a critical public health problem worldwide. To understand pertussis pathogenesis and the host response to both the pathogen and vaccines, a suitable pertussis animal model, particularly
Wenwen Jiang +14 more
doaj +1 more source
Bordetella pertussisand Pertussis Vaccines [PDF]
Bordetella pertussis is a human-specific pathogen that causes whooping cough. The use of pertussis whole-cell vaccines in infants and toddlers led to decreased circulation of the bacterium in the child population and a marked decrease in the incidence of the disease. However, vaccine does not result in life-long immunity; indeed, the circulation of the
openaire +2 more sources
Pertussis is a respiratory infection caused by the Gram-negative bacterium Bordetella pertussis. Despite high vaccination coverage this disease remains a public health concern worldwide.
Michiel M. Kroes +9 more
doaj +1 more source

