Results 41 to 50 of about 125,197 (248)
Adenosine, ‘pertussis-sensitive’ G-proteins, and K+ conductance in central mammalian neurones under energy deprivation [PDF]
There is a striking similarity between the effects of adenosine and of hypoxia or glucose depletion on membrane potential and conductance of hippocampal neurones in tissue slices of rat brain.
A. Spuler +15 more
core +1 more source
Prior to the COVID-19 pandemic, Bordetella pertussis strains not producing pertactin were globally increasing, especially in countries using the acellular pertussis vaccine. Subsequently, during the pandemic, global pertussis incidence dropped to extreme
Helena Martini +6 more
doaj +1 more source
Brain damage following whooping cough vaccination : is it time to lay the myth to rest? [PDF]
Whooping cough causes significant morbidity and mortality, especially in early infancy. Although an effective vaccine exists, vaccine uptake in Malta was previously disappointing due to the general public’s and the medical community’s doubts regarding ...
Busuttil, Ray, Grech, Victor E.
core
Infant rhesus macaques as a non-human primate model of Bordetella pertussis infection
Background The prevalent resurgence of pertussis has recently become a critical public health problem worldwide. To understand pertussis pathogenesis and the host response to both the pathogen and vaccines, a suitable pertussis animal model, particularly
Wenwen Jiang +14 more
doaj +1 more source
Since 1997, an unexpected 2-5-fold increase in the incidence of pertussis has been reported in Poland in comparison with the previous 10 years, although the introduction of the diphtheria-tetanus-pertussis (DTP) vaccination in 1960 reduced the incidence of pertussis approximately 100-fold in the 1980s.
Anna, Gzyl +4 more
openaire +2 more sources
Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley +1 more source
Bordetella pertussis Strains with Increased Toxin Production Associated with Pertussis Resurgence
Before childhood vaccination was introduced in the 1940s, pertussis was a major cause of infant death worldwide. Widespread vaccination of children succeeded in reducing illness and death.
Frits R. Mooi +10 more
doaj +1 more source
Pertussis is a respiratory infection caused by the Gram-negative bacterium Bordetella pertussis. Despite high vaccination coverage this disease remains a public health concern worldwide.
Michiel M. Kroes +9 more
doaj +1 more source
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park +11 more
wiley +1 more source
Ca2+-Stimulated Catecholamine Release from alpha-Toxin Permeabilized PC12 Cells [PDF]
Two possible cellular pathways of catecholamines from the chromaffin vesicles of PC 12 cells to the surrounding medium are explored in this study. The direct one circumventing the cytoplasm can be activated in a-toxin-permeabilized cells with micromolar ...
Ahnert-Hilger, G. +2 more
core +1 more source

