Results 11 to 20 of about 50,642 (200)

Rare manifestations of cutaneous diphtheria: a case report [PDF]

Journal of Medical Case Reports
Background This case report presents an exceptionally rare and atypical presentation of diphtheria in a 17-year-old female of Hausa ethnicity residing in an area with an elevated incidence within Kano State, Nigeria.
Salma Ali Suwaid, Aliyu Mustapha, Monika Ried, Ruqayyah Ali Muhammad, Aminu Shehu Liman, Salma Yusuf   +5 more
doaj   +2 more sources

Challenges of Diphtheria Toxin Detection [PDF]

Toxins
Diphtheria toxin (DT) is the main virulence factor of Corynebacterium diphtheriae, C. ulcerans and C. pseudotuberculosis. Moreover, new Corynebacterium species with the potential to produce diphtheria toxin have also been described.
Marta Prygiel, Ewa Mosiej, Maciej Polak, Katarzyna Krysztopa-Grzybowska, Karol Wdowiak, Kamila Formińska, Aleksandra A. Zasada   +6 more
doaj   +2 more sources

Passive Immunisation in the Treatment of Infectious Diseases Related to Highly Potent Bacterial Toxins [PDF]

Biomedicines
The discovery of microbial toxins as the primary factors responsible for disease manifestations and the discovery that these toxins could be neutralised by antitoxins are linked to the birth of immunology. In the late 19th century, the serum or plasma of
Marta Prygiel, Ewa Mosiej, Karol Wdowiak, Aleksandra Anna Zasada   +3 more
doaj   +2 more sources

Antimicrobial Susceptibility of Toxin-Producing Corynebacterium diphtheriae and C. ulcerans in Belgium [PDF]

Antibiotics
Background/Objectives: Despite a significant reduction in diphtheria incidence and mortality due to vaccination, antitoxin therapy and antibiotic treatments, a concerning resurgence is occurring in Europe.
Zan Janssen, Helena Martini, Robin Vanstokstraeten, Kristof Vandoorslaer, Ingrid Wybo, Eveline Van Honacker, Denis Piérard   +6 more
doaj   +2 more sources

Identification of a human monoclonal antibody to replace equine diphtheria antitoxin for treatment of diphtheria intoxication. [PDF]

Infect Immun, 2013
Sevigny LM, Booth BJ, Rowley KJ, Leav BA, Cheslock PS, Garrity KA, Sloan SE, Thomas W, Babcock GJ, Wang Y.   +9 more
europepmc   +2 more sources

An enhanced intracellular delivery platform based on a distant diphtheria toxin homolog that evades pre-existing antitoxin antibodies [PDF]

EMBO Molecular Medicine
Targeted intracellular delivery of therapeutic proteins remains a significant unmet challenge in biotechnology. A promising approach is to leverage the intrinsic capabilities of bacterial toxins like diphtheria toxin (DT) to deliver a potent cytotoxic ...
Shivneet K Gill, Seiji N Sugiman-Marangos, Greg L Beilhartz, Elizabeth Mei, Mikko Taipale, Roman A Melnyk   +5 more
doaj   +2 more sources

FATAL ANAPHYLAXIS FOLLOWING PROPHYLACTIC INJECTION OF DIPHTHERIA ANTITOXIN SUBCUTANEOUSLY [PDF]

British medical journal, 1919
Andrew D. McCallum
openalex   +2 more sources

Diphtheria in Children- Clinical Profile of Cases during an Outbreak in Kerala, India [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Diphtheria is an acute potentially fatal infectious disease caused by the toxigenic strains of Corynebacterium diphtheriae. Acute respiratory obstruction, toxic myocarditis and neurologic weakness are the most important complications of ...
Thekkile Gangadharan Sindhu, Madhava Vijayakumar, Peethambaran Geetha, Chandran Priya, Puduvail Moorkoth Anitha   +4 more
doaj   +1 more source

Adverse events following the administration of diphtheria antitoxin (Equine Source): An observational study in an Indian tertiary care centre

PANACEA JOURNAL OF MEDICAL SCIENCES, 2022
To assess the clinical safety of diphtheria antitoxin in patients with probable and confirmed diphtheria infection. This was a single-center, observational study which included patients with probable and/or confirmed diphtheria infection.
T. Reddy, M. A. Kumar, K. Shankar
semanticscholar   +1 more source

Diphtheria: A case series from West Maharashtra, India

Journal of Medical Sciences and Health, 2022
Diphtheria is an acute infectious toxin mediated disease caused by Corynebacterium diphtheriae. Effective vaccination has decreased the incidence of disease globally. However, despite of a full-fledged Universal Immunization Programme, the cases
Snehal Patil, Manoj Vedpathak, Sujata Dharmshale, Nasira Shaikh   +3 more
doaj   +1 more source